Zeprumetostat
Tier C — Watch / tradeZeprumetostat
Targets：EZH2
Indications (approved)：Peripheral T-cell lymphoma
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Zeprumetostat-001 | 612-19-1 | 2-ethylbenzoic acid |
| Zeprumetostat-002 | 1261658-58-5 | 2-ethyl-6-iodobenzoic acid |
| Zeprumetostat-003 | 2319580-35-1 | 3,5-dibromo-2-ethyl-6-iodobenzoic acid |
| Zeprumetostat-004 | 5799-75-7 | 1-(prop-2-yn-1-yl)piperidine |
| Zeprumetostat-005 | - | 6-bromo-5-ethyl-2-(piperidin-1-ylmethyl)benzofuran-4-carboxylic acid hydrogen chloride |
| Zeprumetostat-006 | 38041-19-9 | tetrahydro-2H-pyran-4-amine |
| Zeprumetostat-007 | - | 5-ethyl-2-(piperidin-1-ylmethyl)-6-((tetrahydro-2H-pyran-4-yl)amino)benzofuran-4-carboxylic acid |
| Zeprumetostat-008 | - | 5-ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-(piperidin-1-ylmethyl)benzofuran-4-carboxylic acid |
| Zeprumetostat-009 | 1173081-96-3Available | 3-(aminomethyl)-4,6-dimethylpiperidin-2-one hydrogen chloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| Zeprumetostat-005 | - | 6-bromo-5-ethyl-2-(piperidin-1-ylmethyl)benzofuran-4-carboxylic acid hydrogen chloride |
| Zeprumetostat-010 | 771579-27-2 | 3-(aminomethyl)-4,6-dimethylpyridin-2(1H)-one |
| Zeprumetostat-011 | - | 6-bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-ethyl-2-(piperidin-1-ylmethyl)benzofuran-4-carboxamide |
| Zeprumetostat-006 | 38041-19-9 | tetrahydro-2H-pyran-4-amine |
| Zeprumetostat-012 | - | N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-ethyl-2-(piperidin-1-ylmethyl)-6-((tetrahydro-2H-pyran-4-yl)amino)benzofuran-4-carboxamide |
| Code | CAS No. | Intermediate |
|---|---|---|
| Zeprumetostat-013 | 123-07-9 | 4-ethylphenol |
| Zeprumetostat-014 | 1515-95-3 | 1-ethyl-4-methoxybenzene |
| Zeprumetostat-015 | 29643-54-7 | 1-(5-ethyl-2-methoxyphenyl)ethan-1-one |
| Zeprumetostat-016 | 67291-61-6 | 5-ethyl-2-methoxyaniline |
| Zeprumetostat-017 | - | 4-ethyl-7-methoxyindoline-2,3-dione |
| Zeprumetostat-018 | - | methyl 2-amino-6-ethyl-3-methoxybenzoate |
| Zeprumetostat-019 | - | methyl 2-amino-5-bromo-6-ethyl-3-methoxybenzoate |
| Zeprumetostat-020 | - | methyl 3-bromo-2-ethyl-6-iodo-5-methoxybenzoate |
| Zeprumetostat-021 | - | methyl 3-bromo-2-ethyl-5-hydroxy-6-iodobenzoate |
| Zeprumetostat-004 | 5799-75-7 | 1-(prop-2-yn-1-yl)piperidine |
| Zeprumetostat-022 | - | methyl 6-bromo-5-ethyl-2-(piperidin-1-ylmethyl)benzofuran-4-carboxylate |
| Zeprumetostat-005 | - | 6-bromo-5-ethyl-2-(piperidin-1-ylmethyl)benzofuran-4-carboxylic acid hydrogen chloride |
Frequently asked questions
What are the approved indications of Zeprumetostat?
Approved indications include: Peripheral T-cell lymphoma.
When does the Zeprumetostat patent expire?
No public expiry year is available for Zeprumetostat yet; this page updates once verified.
How many synthesis routes are recorded for Zeprumetostat?
3 synthesis routes are recorded; the shortest is 3 steps with 5.0 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Zeprumetostat intermediates?
1 intermediate CAS of Zeprumetostat are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Zeprumetostat intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-22