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Fosmanogepix

Tier C — Watch / trade

Fosmanogepix

Eisai Co., Ltd.
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:Phosphatidylinositol-glycan biosynthesis class W protein

Indications (approved):Candidaemia, 侵袭性真菌感染, 侵袭性念珠菌病, Candidiasis, Hepatic function decline, Fungal infection, Acute myeloid leukaemia

Regional status

US
Phase III
2024-12-12
EU
Phase III
2024-12-12
China
Phase III
2026-04-04
Japan
-

Synthetic routes & intermediates2 routes

Originator routes × 2Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 7 · Total yield 380 mg (Fosmanogepix)
Fosmanogepix-001589-29-7Fosmanogepix-002372-48-5Fosmanogepix-003936342-24-4Fosmanogepix-004936342-25-5Fosmanogepix-005936342-26-6Fosmanogepix-006936342-27-7Fosmanogepix-007936342-28-8Fosmanogepix-00867346-74-1Fosmanogepix-009936339-60-5Fosmanogepix-010229625-50-7API · Fosmanogepix
CodeCAS No.Intermediate
Fosmanogepix-001589-29-71,4-phenylenedimethanol
Fosmanogepix-002372-48-52-fluoropyridine
Fosmanogepix-003936342-24-4(4-((pyridin-2-yloxy)methyl)phenyl)methanol
Fosmanogepix-004936342-25-54-((pyridin-2-yloxy)methyl)benzaldehyde
Fosmanogepix-005936342-26-6(E)-2-((4-(2-nitrovinyl)benzyl)oxy)pyridine
Fosmanogepix-006936342-27-72-((4-(2-nitroethyl)benzyl)oxy)pyridine
Fosmanogepix-007936342-28-8(Z)-N-hydroxy-2-(4-((pyridin-2-yloxy)methyl)phenyl)acetimidoyl chloride
Fosmanogepix-00867346-74-13-ethynylpyridin-2-amine
Fosmanogepix-009936339-60-53-(3-(4-((pyridin-2-yloxy)methyl)benzyl)isoxazol-5-yl)pyridin-2-amine
Fosmanogepix-010229625-50-7Availabledi-tert-butyl (chloromethyl) phosphate
OriginatorRoute 1Steps 7 · Total yield 380 mg (Fosmanogepix)
CodeCAS No.Intermediate

Frequently asked questions

What are the approved indications of Fosmanogepix?

Approved indications include: Candidaemia, 侵袭性真菌感染, 侵袭性念珠菌病, Candidiasis, Hepatic function decline, Fungal infection, Acute myeloid leukaemia.

When does the Fosmanogepix patent expire?

No public expiry year is available for Fosmanogepix yet; this page updates once verified.

How many synthesis routes are recorded for Fosmanogepix?

2 synthesis routes are recorded; the shortest is 7 steps with 380 mg (Fosmanogepix) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Fosmanogepix intermediates?

1 intermediate CAS of Fosmanogepix are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Fosmanogepix intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-22