Bemnifosbuvir
Tier C — Watch / tradeBemnifosbuvir
Targets：NS5B, RdRp
Indications (approved)：Hepatitis C, COVID-19, Liver cirrhosis, Chronic hepatitis C, Hepatic function decline, Renal impairment
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| AT-527-001 | 874638-80-9Available | ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate |
| AT-527-002 | 1199809-24-9 | ((2R,3R,4R,5R)-3-(benzoyloxy)-5-bromo-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate |
| AT-527-003 | 10310-21-1 | 6-chloro-9H-purin-2-amine |
| AT-527-004 | 1199809-26-1 | (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate |
| AT-527-005 | 1998705-62-6 | (2R,3R,4R,5R)-5-(2-amino-6-(methylamino)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-ol |
| AT-527-006 | 1256490-52-4 | isopropyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-D-alaninate |
Frequently asked questions
What are the approved indications of Bemnifosbuvir?
Approved indications include: Hepatitis C, COVID-19, Liver cirrhosis, Chronic hepatitis C, Hepatic function decline, Renal impairment.
When does the Bemnifosbuvir patent expire?
No public expiry year is available for Bemnifosbuvir yet; this page updates once verified.
How many synthesis routes are recorded for Bemnifosbuvir?
1 synthesis routes are recorded; the shortest is 4 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Bemnifosbuvir intermediates?
1 intermediate CAS of Bemnifosbuvir are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Bemnifosbuvir intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-22