Resiniferatoxin

Tier C — Watch / trade

Resiniferatoxin

National Institute of Health, Islamabad

Originator

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：TRPV1

Indications (approved)：Osteoarthritis, 顽固性疼痛, 慢性膝关节痛, Knee arthritis, Morton神经瘤, Cancer pain, Pain, 间质性膀胱炎

Regional status

Phase III

2022-09-15

Phase III

2022-08-26

China

Japan

Phase III

2022-08-26

Synthetic routes & intermediates1 routes

Originator routes × 0Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 1 · Total yield /

Resiniferatoxin57444-62-9Resiniferatoxin-00157852-42-3Resiniferatoxin-002306-08-1API · Resiniferatoxin

Code	CAS No.	Intermediate
Resiniferatoxin	57444-62-9	Benzeneacetic acid, 4-hydroxy-3-methoxy-, [(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]methyl ester
Resiniferatoxin-001	57852-42-3	(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-2-benzyl-6a-hydroxy-5-(hydroxymethyl)-8,10-dimethyl-11a-(prop-1-en-2-yl)-6,6a,9a,10,11,11a-hexahydro-3aH-2,9b-epoxyazuleno[5',4':3,4]benzo[1,2-d][1,3]dioxol-7(3bH)-one
Resiniferatoxin-002	306-08-1	2-(4-hydroxy-3-methoxyphenyl)acetic acid

Frequently asked questions

What are the approved indications of Resiniferatoxin?

Approved indications include: Osteoarthritis, 顽固性疼痛, 慢性膝关节痛, Knee arthritis, Morton神经瘤, Cancer pain, Pain, 间质性膀胱炎.

When does the Resiniferatoxin patent expire?

No public expiry year is available for Resiniferatoxin yet; this page updates once verified.

How many synthesis routes are recorded for Resiniferatoxin?

1 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Resiniferatoxin intermediates?

All intermediates in Resiniferatoxin routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Resiniferatoxin intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-22