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Momelotinib Dihydrochloride

Tier C — Watch / trade

Momelotinib Dihydrochloride

Gilead Sciences Inc
Originator
2023
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:JAK2, ACVR1, JAK1

Brand:Omjjara, Ojjaara

Indications (approved):Myelofibrosis, Myeloproliferative neoplasm, Splenomegaly, Anaemia

Regional status

US
Approved
2023-09-15
EU
Approved
2024-01-25
China
-
Japan
Approved
2024-06-24

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 5 · Total yield 31.69 g
MOME-0013934-20-1MOME-0024334-88-7MOME-003499195-60-7MOME-0042524-67-6MOME-0051056634-62-8MOME-006945749-71-3MOME-0076011-14-9API · Momelotinib Dihydrochloride
CodeCAS No.Intermediate
MOME-0013934-20-1Available2,4-dichloropyrimidine
MOME-0024334-88-7(4-(ethoxycarbonyl)phenyl)boronic acid
MOME-003499195-60-7ethyl 4-(2-chloropyrimidin-4-yl)benzoate
MOME-0042524-67-64-morpholinoaniline
MOME-0051056634-62-8ethyl 4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzoate
MOME-006945749-71-3Available4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzoic acid
MOME-0076011-14-9Available2-aminoacetonitrile hydrochloride

Frequently asked questions

What are the approved indications of Momelotinib Dihydrochloride?

Approved indications include: Myelofibrosis, Myeloproliferative neoplasm, Splenomegaly, Anaemia.

When does the Momelotinib Dihydrochloride patent expire?

No public expiry year is available for Momelotinib Dihydrochloride yet; this page updates once verified.

How many synthesis routes are recorded for Momelotinib Dihydrochloride?

1 synthesis routes are recorded; the shortest is 5 steps with 31.69 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Momelotinib Dihydrochloride intermediates?

3 intermediate CAS of Momelotinib Dihydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Momelotinib Dihydrochloride intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-22