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CAS 2675-89-0
2-chloro-N,N-dimethylacetamide
Codes: FIMA-010, EVENA-006
Application context (from source-drug indications)
Essential hypertensionAmlodipine Besylate/Fimasartan PotassiumHypertensionAmlodipine Besylate/Fimasartan PotassiumHypertensionFimasartan Potassium TrihydrateEssential hypertensionFimasartan Potassium TrihydrateHypercholesterolaemiaFimasartan Potassium TrihydrateChronic renal impairmentFimasartan Potassium TrihydrateRenal impairmentFimasartan Potassium TrihydrateHepatic function declineFimasartan Potassium TrihydrateSchizophreniaEvenamide Hydrochloride精神疾病Evenamide Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Amlodipine Besylate/Fimasartan Potassium | Tier C — Watch / trade | - |
| Fimasartan Potassium Trihydrate | Tier C — Watch / trade | - |
| Evenamide Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
5-(4'-(bromomethyl)-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole→2-(2-butyl-4-methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1,6-dihydropyrimidin-5-yl)-N,N-dimethylacetamide→methyl 3-oxobutanoate→2-chloro-N,N-dimethylacetamide→methyl 2-acetyl-4-(dimethylamino)-4-oxobutanoate→ pentanimidamide;hydrochloride→methyl 2-acetyl-4-(dimethylamino)-4-oxobutanoate
5-(4'-(bromomethyl)-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole→2-(2-butyl-4-methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1,6-dihydropyrimidin-5-yl)-N,N-dimethylacetamide→methyl 3-oxobutanoate→2-chloro-N,N-dimethylacetamide→methyl 2-acetyl-4-(dimethylamino)-4-oxobutanoate→ pentanimidamide;hydrochloride→methyl 2-acetyl-4-(dimethylamino)-4-oxobutanoate
2-(3-(benzyloxy)phenyl)ethan-1-amine hydrochloride→tert-butyl (3-(benzyloxy)phenethyl)carbamate→tert-butyl (3-hydroxyphenethyl)carbamate→1-bromobutane→tert-butyl (3-butoxyphenethyl)carbamate→2-chloro-N,N-dimethylacetamide→tert-butyl (3-butoxyphenethyl)(2-(dimethylamino)-2-oxoethyl)carbamate→Evenamide Hydrochloride
Intermediates available on this site
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