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CAS 3978-80-1
(tert-butoxycarbonyl)-L-tyrosine(S)-2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid(2S)-3-(4-Hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
Codes: GADO-003, YSV-005, (IIIb)1062329-1-a
Application context (from source-drug indications)
Contrast imagingGadoxetate DisodiumDiagnostic agentGadoxetate DisodiumProstate cancerGadoxetate DisodiumCastration-resistant prostate cancerGadoxetate DisodiumLiver cancerGadoxetate DisodiumHepatocellular carcinomaGadoxetate DisodiumNon-small cell lung cancerTyroservaltide
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Gadoxetate Disodium | Tier C — Watch / trade | - |
| Tyroservaltide | Tier C — Watch / trade | - |
| Dazdotuftide | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
L-tyrosine→(tert-butoxycarbonyl)-L-tyrosine→(S)-2-((tert-butoxycarbonyl)amino)-3-(4-ethoxyphenyl)propanoic acid→tert-butyl (S)-(1-(4-ethoxyphenyl)-3-hydroxypropan-2-yl)carbamate→(S)-2-((tert-butoxycarbonyl)amino)-3-(4-ethoxyphenyl)propyl methanesulfonate→tert-butyl (S)-(1-((2-aminoethyl)amino)-3-(4-ethoxyphenyl)propan-2-yl)carbamate→(S)-N1-(2-aminoethyl)-3-(4-ethoxyphenyl)propane-1,2-diamine hydrochloride→di-tert-butyl 2,2'-((2-((2-(bis(2-(tert-butoxy)-2-oxoethyl)amino)-3-(4-ethoxyphenyl)propyl)(2-(tert-butoxy)-2-oxoethyl)amino)ethyl)azanediyl)(S)-diacetate→Gadoxetate sodium
(tert-butoxycarbonyl)-L-serine→methyl L-valinate hydrochloride→methyl (tert-butoxycarbonyl)-L-seryl-L-valinate→methyl L-seryl-L-valinate hydrochloride→(S)-2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid→methyl (tert-butoxycarbonyl)-L-tyrosyl-L-seryl-L-valinate→(tert-butoxycarbonyl)-L-tyrosyl-L-seryl-L-valine
4-Aminophenyl 2-(trimethylammonio)ethyl phosphate→4-Diazoniophenyl 2-(trimethylazaniumyl)ethyl phosphate chloride→(2S)-3-(4-Hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid→N-[[(9H-Fluoren-9-yl)methoxy]carbonyl]-3-[(E)-[4-([[2-(trimethylazaniumyl)ethoxy]phosphinato]oxy)phenyl]diazenyl]-L-tyrosine→N-(tert-Butoxycarbonyl)-3-[(E)-[4-([[2-(trimethylazaniumyl)ethoxy]phosphinato]oxy)phenyl]diazenyl]-L-tyrosine→Resin bound 3-[(E)-[4-([[2-(trimethylazaniumyl)ethoxy]phosphinato]oxy)phenyl]diazenyl]-L-tyrosine→2-(9H-Fluoren-9-ylmethoxycarbonylamino)acetic acid→2-((tert-Butoxycarbonyl)amino)acetic acid→Resin bound glycyl-3-[(E)-[4-([[2-(trimethylazaniumyl)ethoxy]phosphinato]oxy)phenyl]diazenyl]-L-tyrosine→(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[2-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-sulfonyl)carbamimidamido]pentanoic acid→(2S)-2-{[(tert-Butoxy)carbonyl]amino}-5-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}pentanoic acid→Resin bound N5-[N-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-sulfonyl)carbamimidoyl]-L-ornithylglycyl-3-[(E)-[4-([[2-(trimethylazaniumyl)ethoxy]phosphinato]oxy)phenyl]diazenyl]-L-tyrosine
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.