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CAS 5470-70-2
methyl 6-methylnicotinate
Codes: ETOR-008, HYPIL-001
Application context (from source-drug indications)
OsteoarthritisEtoricoxib痛风性关节炎EtoricoxibDysmenorrhoeaEtoricoxibRheumatoid arthritisEtoricoxibAnkylosing spondylitisEtoricoxibParkinson's diseaseEtoricoxib肾上腺脑白质营养不良LeriglitazoneFriedreich's ataxiaLeriglitazone
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Etoricoxib | Tier C — Watch / trade | - |
| Leriglitazone | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
methyl 6-methylnicotinate→N-methoxy-N,6-dimethylnicotinamide→6-methylnicotinaldehyde→diphenyl ((6-methylpyridin-3-yl)(phenylamino)methyl)phosphonate→4-(methylsulfonyl)benzaldehyde→(E)-N-(1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)vinyl)aniline→1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)ethan-1-one→ETOR-015→(Z)-4-chloro-3,5-bis(dimethylamino)-1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)pent-4-en-1-one→(2Z,4Z)-4-chloro-5-(dimethylamino)-1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)penta-2,4-dien-1-one
5-(4-(2-(5-(1-(methoxymethoxy)ethyl)pyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione→Hydroxypioglitazone→methyl 6-methylnicotinate→1-(6-methylpyridin-3-yl)ethanone→1-(6-methylpyridin-3-yl)ethanol→5-(1-(methoxymethoxy)ethyl)-2-methylpyridine→2-(5-(1-(methoxymethoxy)ethyl)pyridin-2-yl)ethanol→4-hydroxybenzaldehyde→4-(2-(5-(1-(methoxymethoxy)ethyl)pyridin-2-yl)ethoxy)benzaldehyde→thiazolidine-2,4-dione→(E)-5-(4-(2-(5-(1-(methoxymethoxy)ethyl)pyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione
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