← Back to patent-cliff list
CAS 552-89-6
2-Nitrobenzaldehydeo-Nitrobenzaldehyde2-nitrobenzaldehyde
Codes: Ambroxol- 005, Vazegepant-005
Application context (from source-drug indications)
Chronic bronchitisRoxithromycin/Ambroxol HydrochlorideBronchitisRoxithromycin/Ambroxol HydrochlorideRespiratory tract infectionRoxithromycin/Ambroxol HydrochloridePneumoniaRoxithromycin/Ambroxol HydrochlorideTracheitisRoxithromycin/Ambroxol HydrochlorideBacterial infectionRoxithromycin/Ambroxol HydrochlorideAnaesthesiaAmbroxol HydrochloridePharyngitisAmbroxol HydrochlorideRespiratory diseaseAmbroxol HydrochlorideBronchitisAmbroxol HydrochlorideParkinson's diseaseAmbroxol HydrochlorideParkinsonismAmbroxol HydrochlorideMigraineZavegepantMigraine without auraZavegepant有先兆的偏头痛ZavegepantCluster headacheZavegepantAsthmaZavegepantCOVID-19Zavegepant
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Roxithromycin/Ambroxol Hydrochloride | Tier C — Watch / trade | - |
| Ambroxol Hydrochloride | Tier C — Watch / trade | - |
| Zavegepant | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
trans-4-Aminocyclohexanol→2,4-Dihydro-1H-3,1-benzoxazine-2,4-dione→trans-2-Amino-N-(4-hydroxycyclohexyl)benzamide→trans-4-(2-Aminobenzylamino)cyclohexanol→2-Nitrobenzaldehyde→trans-4-(2-Nitrophenylmethyleneamino)cyclohexanol
3,5-Dibromo-2-nitrobenzaldehyde→trans-4-(2-Nitro-3,5-dibromobenzylideneamino)cyclohexanol→(2-Amino-3,5-dibromophenyl)methyl 1H-imidazole-1-carboxylate→o-Nitrobenzaldehyde→trans-4-Aminocyclohexanol→2-Amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine
trans-4-Aminocyclohexanol→2,4-Dihydro-1H-3,1-benzoxazine-2,4-dione→trans-2-Amino-N-(4-hydroxycyclohexyl)benzamide→trans-4-(2-Aminobenzylamino)cyclohexanol→2-Nitrobenzaldehyde→trans-4-(2-Nitrophenylmethyleneamino)cyclohexanol
3,5-Dibromo-2-nitrobenzaldehyde→trans-4-(2-Nitro-3,5-dibromobenzylideneamino)cyclohexanol→(2-Amino-3,5-dibromophenyl)methyl 1H-imidazole-1-carboxylate→o-Nitrobenzaldehyde→trans-4-Aminocyclohexanol→2-Amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Qualified Partner — East China API Works | (R)-METHYL 2-(((BENZYLOXY)CARBONYL)AMINO)-3-(7-METHYL-1H-INDAZOL-5-YL)PROPANOATE Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | 3-(piperidin-4-yl)quinolin-2(1h)-one hydrochloride Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | 3-(piperidin-4-yl)quinolin-2(1h)-one Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 1-(1-Methyl-4-piperidinyl)piperazine Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | 1H-Indazole-5-propanoic acid,α-amino-7-methyl-,methyl ester, (αR)- Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 1-(1-METHYLPIPERIDIN-4-YL)PIPERAZINE 3HCL Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.