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CAS 79617-96-2
(1S,4S)-4-(3,4-Dichlorophenyl)-N-methyltetralin-1-amine
Codes: Sertraline Hydrochloride-025
Application context (from source-drug indications)
Obsessive-compulsive disorderSertraline Citrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Sertraline Citrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Benzene→3,4-Dichlorobenzoyl chloride→(3,4-Dichlorophenyl)(phenyl)methanone→1,2-Dichloro-4-(1-phenylethenyl)benzene→Butane-1,4-dioic acid diethyl diester→1,4-Diethyl (2Z)-2-[(3,4-dichlorophenyl)(phenyl)methylidene]butanedioate→4-(3,4-Dichlorophenyl)-4-phenylbut-3-enoic acid→4-(3,4-Dichlorophenyl)-4-phenylbutanoic acid→4-(3,4-Dichlorophenyl)-4-phenylbutanoyl chloride→4-(3,4-Dichlorophenyl)-1-tetralone→4-(2,3-Dichlorophenyl)-1-tetralone→1,2-Dichlorobenzene→Aminomethane→N-[(1E)-4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-ylidene]methanamine→(1S,4S)-4-(3,4-Dichlorophenyl)-N-methyltetralin-1-amine
(1R)-1,2-dihydronaphthalen-1-ol→tert-Butyl[(1R)-1,2-dihydronaphthalen-1-yloxy]diphenylsilane→[[(1R)-4-Bromo-1,2-dihydronaphthalen-1-yl]oxy](tert-butyl)diphenylsilane→(3,4-Dichlorophenyl)(trimethyl)stannane→3,4-Dichlorophenol→3,4-Dichlorophenyl trifluoromethanesulfonate→tert-Butyl[[(1R)-4-(3,4-dichlorophenyl)-1,2-dihydronaphthalen-1-yl]oxy]diphenylsilane→(3,4-Dichlorophenyl)boronic acid→(1R)-4-(3,4-Dichlorophenyl)-1,2-dihydronaphthalen-1-ol→(1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-ol→(1S,4S)-1-Azido-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalene→4(S)-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1(S)-amine→Carbonochloridic acid ethyl ester→Ethyl [(1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamate→(1S,4S)-4-(3,4-Dichlorophenyl)-N-methyltetralin-1-amine
1-Hydroxynaphthalene→1,2-Dichlorobenzene→4(S)-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-one→N-Methylhydroxylamine→1-(3,4-dichlorophenyl)-4-(methylnitroso)-1,2,3,4-tetrahydronaphthalene→(1S,4S)-4-(3,4-Dichlorophenyl)-N-methyltetralin-1-amine
4-(3,4-Dichlorophenyl)-1-tetralone→Aminomethane→N-[(1E)-4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-ylidene]methanamine→(±)-cis-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine→(1S,4S)-4-(3,4-Dichlorophenyl)-N-methyltetralin-1-amine→(2R)-Hydroxy(phenyl)acetic acid (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
4-(3,4-Dichlorophenyl)-1-tetralone→Aminomethane→N-[(1E)-4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-ylidene]methanamine→(±)-cis/trans 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine→(±)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine→(1S,4S)-4-(3,4-Dichlorophenyl)-N-methyltetralin-1-amine
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