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CAS 86-74-8
9H-carbazole
Codes: CHIG-006, CBL-0137-005
Application context (from source-drug indications)
Type 2 diabetesChiglitazar SodiumNon-alcoholic steatohepatitisChiglitazar SodiumInsulin resistanceChiglitazar SodiumHepatic function declineChiglitazar SodiumRenal impairmentChiglitazar SodiumDiabetesChiglitazar Sodium
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Chiglitazar Sodium | Tier C — Watch / trade | - |
| CBL-0137 | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
CHIG-001→(S)-methyl 2-amino-3-(4-hydroxyphenyl)propanoate→CHIG-003→1,2-dibromoethane→(S)-3-(4-(2-bromoethoxy)phenyl)-2-((2-(4-fluorobenzoyl)phenyl)amino)propanoic acid→9H-carbazole
1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one) hydrochloride→2-aminoethan-1-ol→N-(2-hydroxyethyl)-4-nitrobenzenesulfonamide→2-((4-nitrophenyl)sulfonamido)ethyl methanesulfonate→1-((4-nitrophenyl)sulfonyl)aziridine→9H-carbazole→N-(2-(9H-carbazol-9-yl)ethyl)-4-nitrobenzenesulfonamide→N-(2-(3,6-diacetyl-9H-carbazol-9-yl)ethyl)-4-nitrobenzenesulfonamide→1,1'-(9-(2-aminoethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)→1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)
1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one) hydrochloride→9H-carbazole→1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)→2-(isopropylamino)ethanol→tert-butyl (2-hydroxyethyl)(isopropyl)carbamate→3-isopropyloxazolidin-2-one→1,1'-(9H-carbazole-3,6-diyl)bis(ethan-1-one)
Intermediates available on this site
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.