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CAS 54060-30-9
3-ethynylaniline
登记编号：ICOT-009、NRC-2694-005
应用背景（按来源药适应症）
非小细胞肺癌盐酸埃克替尼肺腺癌盐酸埃克替尼支气管肿瘤盐酸埃克替尼肺癌盐酸埃克替尼转移性乳腺癌盐酸埃克替尼银屑病盐酸埃克替尼转移性上皮癌NRC-2694
来源药（使用该中间体的合成路线）
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
2,2'-(ethane-1,2-diylbis(oxy))bis(ethan-1-ol)→(ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate)→ethyl 3,4-dihydroxybenzoate→ethyl 2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carboxylate→ethyl 13-nitro-2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carboxylate→ethyl 13-amino-2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carboxylate hydrochloride→7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4(3H)-one→4-chloro-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazoline→3-ethynylaniline
(ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate)→3-ethynylaniline→3,4-dihydroxybenzonitrile→2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carbonitrile→13-nitro-2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carbonitrile→13-amino-2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carbonitrile→(E)-N'-(13-cyano-2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecin-12-yl)-N,N-dimethylformimidamide
3-ethynylaniline→(E)-3-(3-nitrophenyl)acrylic acid→(2S,3R)-2,3-dibromo-3-(3-nitrophenyl)propanoic acid→1-ethynyl-3-nitrobenzene
6,7-dimethoxyquinazolin-4(3H)-one→6-hydroxy-7-methoxyquinazolin-4(3H)-one→7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl acetate→4-chloro-7-methoxyquinazolin-6-yl acetate hydrochloride→3-ethynylaniline→4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl acetate hydrochloride→4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-ol→4-(3-chloropropyl)morpholine→N-(3-ethynylphenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine hydrochloride
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 | 操作 |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 3-Ethynylaniline Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。