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CAS 67843-74-7
(S)-2-(chloromethyl)oxirane
登记编号：RIVA-030、LAND-009、LINE-023、SUTEZ-010
应用背景（按来源药适应症）
肺栓塞利伐沙班中风利伐沙班先天性心脏缺损利伐沙班血栓形成利伐沙班静脉血栓栓塞利伐沙班冠状动脉疾病利伐沙班室上性心动过速盐酸兰地洛尔室性心律失常盐酸兰地洛尔心律失常盐酸兰地洛尔窦性心动过速盐酸兰地洛尔心房颤动盐酸兰地洛尔心房扑动盐酸兰地洛尔非复杂性皮肤和皮肤结构感染利奈唑胺肺炎利奈唑胺复杂皮肤和皮肤结构感染利奈唑胺菌血症利奈唑胺细菌感染利奈唑胺医疗保健相关性肺炎利奈唑胺结核分枝杆菌感染Sutezolid肺结核Sutezolid
来源药（使用该中间体的合成路线）
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
5-chlorothiophene-2-carbonyl chloride→benzyl (4-(3-oxomorpholino)phenyl)carbamate→(S)-2-(chloromethyl)oxirane→benzaldehyde→(S,E)-1-(benzylideneamino)-3-chloropropan-2-ol→(S)-1-amino-3-chloropropan-2-ol hydrochloride→(S)-5-chloro-N-(3-chloro-2-hydroxypropyl)thiophene-2-carboxamide→(S)-1-chloro-3-(5-chlorothiophene-2-carboxamido)propan-2-yl acetate
4-(4-aminophenyl)morpholin-3-one→5-chlorothiophene-2-carbaldehyde→(S)-2-(chloromethyl)oxirane→(S)-1-azido-3-chloropropan-2-ol→(S)-2-(azidomethyl)oxirane→(R)-4-(4-((3-azido-2-hydroxypropyl)amino)phenyl)morpholin-3-one→(R)-4-(4-(5-(azidomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one→(S)-4-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one
(S)-(2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-hydroxyphenyl)propanoate→(S)-2-(chloromethyl)oxirane→LAND-010→((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-((R)-3-chloro-2-hydroxypropoxy)phenyl)propanoate→N-(2-aminoethyl)morpholine-4-carboxamide oxalate
3-fluoro-4-morpholinoaniline→(R)-5-(azidomethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one→(S)-2-(chloromethyl)oxirane→(S)-1-azido-3-chloropropan-2-ol→(R)-2-(azidomethyl)oxirane→(R)-1-azido-3-((3-fluoro-4-morpholinophenyl)amino)propan-2-ol→(S)-5-(aminomethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one
benzyl (3-fluoro-4-thiomorpholinophenyl)carbamate→4-chlorobenzaldehyde→(S)-2-(chloromethyl)oxirane→(S,E)-1-chloro-3-((4-chlorobenzylidene)amino)propan-2-ol→(S,Z)-5-(((4-chlorobenzylidene)amino)methyl)-3-(3-fluoro-4-thiomorpholinophenyl)oxazolidin-2-one→(S)-5-(aminomethyl)-3-(3-fluoro-4-thiomorpholinophenyl)oxazolidin-2-one→(S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 | 操作 |
|---|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 4-(4-Aminophenyl)morpholin -3-one Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | (S)-(+)-N-(2,3-Epoxypropyl)phthalimide Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | 5-Chlorothiophene-2-carboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | 5-Chlorothiophene-2-carbonyl chloride Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | 2-[[(5S)-2-0x0-3-[4-(3-0xo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | 4-[4-[(5S)-5-(Aminomethyl)-2-0xo-3-oxazolidinyl]phenyl] -3-morpholinone hydrochloride Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | 2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。