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CAS 90-15-3
naphthalen-1-ol
登记编号：NAFT-001、NUC-3373-001、CG-200745-006
应用背景（按来源药适应症）
排尿困难萘哌地尔前列腺增生萘哌地尔增生萘哌地尔结直肠癌Fosifloxuridine nafalbenamide非小细胞肺癌Fosifloxuridine nafalbenamide黑色素瘤Fosifloxuridine nafalbenamide霍奇金病Fosifloxuridine nafalbenamide间皮组织肿瘤Fosifloxuridine nafalbenamide鳞状细胞癌Fosifloxuridine nafalbenamide胰腺癌ivaltinostat骨髓增生异常综合征ivaltinostat实体瘤ivaltinostat纤维化ivaltinostat血液肿瘤ivaltinostat
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 萘哌地尔Naftopidil | Tier C · 观察 / 贸易 | - |
| Fosifloxuridine nafalbenamide | Tier C · 观察 / 贸易 | - |
| ivaltinostat | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
benzyl ((((2R,3S,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(naphthalen-1-yloxy)phosphoryl)-L-alaninate→naphthalen-1-ol→naphthalen-1-yl phosphorodichloridate→benzyl L-alaninate 4-methylbenzenesulfonate→benzyl (chloro(naphthalen-1-yloxy)phosphoryl)-L-alaninate→5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
oxepan-2-one→methyl 6-hydroxyhexanoate→methyl 6-oxohexanoate→1-(tert-butyl) 8-methyl 3-hydroxy-2-methyleneoctanedioate→1-(tert-butyl) 8-methyl (Z)-2-(bromomethyl)oct-2-enedioate→naphthalen-1-ol→1-(tert-butyl) 8-methyl (E)-2-((naphthalen-1-yloxy)methyl)oct-2-enedioate→(E)-8-methoxy-2-((naphthalen-1-yloxy)methyl)-8-oxooct-2-enoic acid→N1,N1-dimethylpropane-1,3-diamine→methyl (E)-8-((3-(dimethylamino)propyl)amino)-7-((naphthalen-1-yloxy)methyl)-8-oxooct-6-enoate→(E)-8-((3-(dimethylamino)propyl)amino)-7-((naphthalen-1-yloxy)methyl)-8-oxooct-6-enoic acid→O-(tetrahydro-2H-pyran-2-yl)hydroxylamine→(E)-N1-(3-(dimethylamino)propyl)-2-((naphthalen-1-yloxy)methyl)-N8-((tetrahydro-2H-pyran-2-yl)oxy)oct-2-enediamide
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。