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Butylidenephthalide

Tier C — Watch / trade

Butylidenephthalide

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Originator
-
First approval
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Expiry (public)
No sales data
Peak sales
Natural product / extract
Type

Targets:AXL, NR4A1, Telomerase

Brand:Cerebraca wafer

Indications (approved):Glioblastoma, Glioma, Amyotrophic lateral sclerosis

Regional status

US
Phase III
2026-01-15
EU
-
China
-
Japan
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Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 1 · Total yield /
BUPHTH-00185-44-9BUPHTH-0022082-59-9Butylidenephthalide551-08-6API · Butylidenephthalide
CodeCAS No.Intermediate
BUPHTH-00185-44-9Availableisobenzofuran-1,3-dione
BUPHTH-0022082-59-9pentanoic anhydride
Butylidenephthalide551-08-6-

Frequently asked questions

What are the approved indications of Butylidenephthalide?

Approved indications include: Glioblastoma, Glioma, Amyotrophic lateral sclerosis.

When does the Butylidenephthalide patent expire?

No public expiry year is available for Butylidenephthalide yet; this page updates once verified.

How many synthesis routes are recorded for Butylidenephthalide?

1 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Butylidenephthalide intermediates?

1 intermediate CAS of Butylidenephthalide are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Butylidenephthalide intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-22