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CAS 111-24-0
1,5-DibromopentanePentamethylene dibromide1,5-dibromopentane
Codes: Eperisone Hydrochloride-006, Cilastatin Sodium-002, GACYC-006
Application context (from source-drug indications)
Back painDiclofenac Sodium/Eperisone HydrochlorideMuscle spasmEperisone HydrochlorideBack painEperisone HydrochlorideLow back painEperisone HydrochlorideInfectious diseaseCilastatin Sodium耳鸣Gacyclidine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Diclofenac Sodium/Eperisone Hydrochloride | Tier C — Watch / trade | - |
| Eperisone Hydrochloride | Tier C — Watch / trade | - |
| Cilastatin Sodium | Tier C — Watch / trade | - |
| Gacyclidine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(4-ethylphenyl)propan-1-one→Piperidine hydrochloride→Hexahydropyridine→3-chloro-1-(4-ethylphenyl)-2-methylpropan-1-one→3-amino-1-(4-ethylphenyl)-2-methylpropan-1-one→1,5-Dibromopentane→Ethylbenzene→2-methyl-3-(piperidin-1-yl)propanoyl chloride→1-(4-ethylphenyl)-2-methylprop-2-en-1-one
1-(4-ethylphenyl)propan-1-one→Piperidine hydrochloride→Hexahydropyridine→3-chloro-1-(4-ethylphenyl)-2-methylpropan-1-one→3-amino-1-(4-ethylphenyl)-2-methylpropan-1-one→1,5-Dibromopentane→Ethylbenzene→2-methyl-3-(piperidin-1-yl)propanoyl chloride→1-(4-ethylphenyl)-2-methylprop-2-en-1-one
Ethyl 1,3-dithiane-2-carboxylate→Pentamethylene dibromide→ethyl 2-(5-bromopentyl)-1,3-dithiane-2-carboxylate→Ethyl 7-bromo-2-oxoheptanoate→7-bromo-2-oxoheptanoic acid→(+)-(1S)-2,2-Dimethylcyclopropanecarboxamide→(2Z)-7-Bromo-2-([[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino)hept-2-enoic acid→Plant-derived natural amino-acid L-cysteine
thiophen-2-ylmagnesium bromide→2-methylcyclohexan-1-one→(2S)-2-methyl-1-(thiophen-2-yl)cyclohexan-1-ol→2-((2S)-1-azido-2-methylcyclohexyl)thiophene→(2S)-2-methyl-1-(thiophen-2-yl)cyclohexan-1-amine→1,5-dibromopentane→1-((2S)-2-methyl-1-(thiophen-2-yl)cyclohexyl)piperidine→1-((1R,2S)-2-methyl-1-(thiophen-2-yl)cyclohexyl)piperidine hydrochloride
Intermediates available on this site
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