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CAS 119532-26-2
1-(2,3-dichlorophenyl)piperazine hydrochloride
Codes: CARI-004, RP-5063-006
Application context (from source-drug indications)
Major depressive disorderCariprazine HydrochlorideSchizophreniaCariprazine HydrochlorideManiaCariprazine HydrochlorideSchizophreniaBrilaroxazineMajor depressive disorderBrilaroxazinePulmonary arterial hypertensionBrilaroxazineIdiopathic pulmonary fibrosisBrilaroxazineManiaBrilaroxazineAttention deficit hyperactivity disorderBrilaroxazine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Cariprazine Hydrochloride | Tier A — Act now | 2029 |
| Brilaroxazine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-bromo-2,3-dichlorobenzene→tert-butyl piperazine-1-carboxylate→tert-butyl 4-(2,3-dichlorophenyl)piperazine-1-carboxylate→1-(2,3-dichlorophenyl)piperazine hydrochloride→tert-butyl ((1r,4r)-4-(2-oxoethyl)cyclohexyl)carbamate→tert-butyl ((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)carbamate→(1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine→dimethylcarbamic chloride
RP-5063→4-methoxy-2-nitrophenol→ethyl 2-(4-methoxy-2-nitrophenoxy)acetate→ethyl 2-(4-hydroxy-2-nitrophenoxy)acetate→1,4-dibromobutane→ethyl 2-(4-(4-bromobutoxy)-2-nitrophenoxy)acetate→1-(2,3-dichlorophenyl)piperazine hydrochloride→ethyl 2-(4-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-nitrophenoxy)acetate→6-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2H-benzo[b][1,4]oxazin-3(4H)-one
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 1-(2,3-Dichlorophenyl)piperazine hydrochloride Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 1-(2,3-Dichlorophenyl)piperazine hydrochloride Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.