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CAS 917-64-6
Iodo(methyl)magnesium
Codes: (XXX)145089-2-d, Nabilone-008
Application context (from source-drug indications)
Alzheimer's diseaseRivastigmine TartrateDementiaRivastigmine TartrateParkinson's diseaseRivastigmine Tartrate抗胆碱能综合征Rivastigmine Tartrate神经行为学表现Rivastigmine TartrateCognitive impairmentRivastigmine TartratePruritusNabiloneEnd-stage renal diseaseNabiloneNauseaNabilone呕吐NabiloneObsessive-compulsive disorderNabiloneSuicidal ideationNabilone
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Rivastigmine Tartrate | Tier B — Position early | - |
| Nabilone | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
N-Boc-[1(S)-(3-Methoxyphenyl)ethyl]-N-methylamine→(3aS,7aS)-2-[(E)-[(3-Methoxyphenyl)methylidene]amino]-1,3-di(propan-2-yl)octahydro-1H-1,3,2lambda5-benzodiazaphosphol-2-one→Iodo(methyl)magnesium→(3aS,7aS)-2-[[(1S)-1-(3-Methoxyphenyl)ethyl]amino]-1,3-di(propan-2-yl)octahydro-1H-1,3,2lambda5-benzodiazaphosphol-2-one→N-Boc-1(S)-(3-Methoxyphenyl)ethanamine→Iodomethane
1,2-Dihydroxyethane→1,5-diethyl 2-acetylpentanedioate→5-(1,1-Dimethylheptyl)benzene-1,3-diol→ethyl 3-[5-hydroxy-4-methyl-7-(2-methyloctan-2-yl)-2-oxo-2H-chromen-3-yl]propanoate→3-hydroxy-5-(2-methyloctan-2-yl)-8-oxatricyclo[8.4.0.0(2,7)]tetradeca-1(10),2(7),3,5-tetraene-9,13-dione→14'-hydroxy-12'-(2-methyloctan-2-yl)-9'-oxaspiro[1,3-dioxolane-2,4'-tricyclo[8.4.0.0(2,7)]tetradecane]-1'(10'),2'(7'),11',13'-tetraen-8'-one→3-hydroxy-9,9-dimethyl-5-(2-methyloctan-2-yl)-8-oxatricyclo[8.4.0.0(2,7)]tetradeca-1(14),2(7),3,5-tetraen-13-one→Iodo(methyl)magnesium
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