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CAS 19009-39-3
N,N-Diisopropylcarbamic chloridediisopropylcarbamic chloride
登记编号：Sertraline Hydrochloride-087、ESCI-024
应用背景（按来源药适应症）
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来源药（使用该中间体的合成路线）
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
Benzaldehyde→Allyl(bromo)magnesium→1-Phenylbut-3-en-1-ol→(1S)-1-Phenylbut-3-en-1-ol→N,N-Diisopropylcarbamic chloride→(1S)-1-Phenylbut-3-en-1-yl dipropan-2-ylcarbamate→2-(3,4-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane→(3,4-Dichlorophenyl)boronic acid→2,3-Dimethyl-2,3-butanediol→2-[(1R)-1-(3,4-Dichlorophenyl)-1-phenylbut-3-en-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane→1,2-Dichloro-4-[(1R)-1-phenylbut-3-en-1-yl]benzene→(4R)-4-(3,4-Dichlorophenyl)-4-phenylbutanoic acid→4(S)-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-one→N-Methylhydroxylamine→N-[(1E,4S)-4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-ylidene]methanamine→(1S,4S)-4-(3,4-Dichlorophenyl)-N-methyltetralin-1-amine
N-methylprop-2-yn-1-amine→tert-butyl methyl(prop-2-yn-1-yl)carbamate→4-fluorobenzaldehyde→tert-butyl (R)-(4-(4-fluorophenyl)-4-hydroxybut-2-yn-1-yl)(methyl)carbamate→tert-butyl (S)-(4-(4-fluorophenyl)-4-hydroxybutyl)(methyl)carbamate→diisopropylcarbamic chloride→(S)-4-((tert-butoxycarbonyl)(methyl)amino)-1-(4-fluorophenyl)butyl diisopropylcarbamate→3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile→tert-butyl (S)-(4-(4-cyano-2-methylphenyl)-4-(4-fluorophenyl)-4-hydroxybutyl)(methyl)carbamate→tert-butyl (S)-(3-(5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-1-yl)propyl)(methyl)carbamate→(S)-1-(4-fluorophenyl)-1-(3-(methylamino)propyl)-1,3-dihydroisobenzofuran-5-carbonitrile→4-bromo-3-methylbenzonitrile
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