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CAS 403-43-0
4-fluorobenzoyl chloride4-Fluoranylbenzoyl chloride
登记编号：FEZO-005、(II)1078735-1-a、(VI)1078735-2-a
应用背景（按来源药适应症）
血管舒缩症非唑奈坦热潮红非唑奈坦绝经期症状非唑奈坦前列腺癌非唑奈坦乳腺癌非唑奈坦肾功能不全非唑奈坦乳腺癌甲苯磺酸依仑司群转移性乳腺癌甲苯磺酸依仑司群转移癌甲苯磺酸依仑司群卵巢癌甲苯磺酸依仑司群子宫内膜癌甲苯磺酸依仑司群结直肠癌甲苯磺酸依仑司群
来源药（使用该中间体的合成路线）
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
4-Bromo-3-chloro-7-methoxyquinoline→4-Fluoranylbenzoyl chloride→(3-Chloro-7-methoxyquinolin-4-yl)(4-fluorophenyl)methanone→(3-Chloro-7-hydroxyquinolin-4-yl)(4-fluorophenyl)methanone→2-[3-(Fluoromethyl)azetidin-1-yl]ethan-1-ol hydrogen chloride→(3-Chloro-7-hydroxyquinolin-4-yl)(4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenyl)methanone→[2-Fluoro-4-(trifluoromethyl)phenyl]boronic acid→(4-[2-[3-(Fluoromethyl)azetidin-1-yl]ethoxy]phenyl)[3-[2-fluoro-4-(trifluoromethyl)phenyl]-7-hydroxyquinolin-4-yl]methanone→4-[(4-[2-[3-(Fluoromethyl)azetidin-1-yl]ethoxy]phenyl)(hydroxy)methyl]-3-[2-fluoro-4-(trifluoromethyl)phenyl]quinolin-7-ol→5-(4-[2-[3-(Fluoromethyl)azetidin-1-yl]ethoxy]phenyl)-8-(trifluoromethyl)-5H-[1]benzopyrano[4,3-c]quinolin-2-ol→3-(Fluoromethyl)azetidine hydrogen chloride→1,4-Dioxane-2,5-diol→2-[3-(Fluoromethyl)azetidin-1-yl]ethan-1-ol
4-Hydroxy-7-methoxyquinoline→3-Chloro-4-hydroxy-7-methoxyquinoline→4-Bromo-3-chloro-7-methoxyquinoline→(4-Fluorophenyl)methanone→(3-Chloro-7-methoxyquinolin-4-yl)(4-fluorophenyl)methanone→4-Fluoranylbenzoyl chloride→(3-Chloro-7-hydroxyquinolin-4-yl)(4-fluorophenyl)methanone→1,1-Diethoxy-2-hydroxyethane→(3-Chloro-7-hydroxyquinolin-4-yl)[4-(2,2-diethoxyethoxy)phenyl]methanone→[2-Fluoro-4-(trifluoromethyl)phenyl]boronic acid→[4-(2,2-Diethoxyethoxy)phenyl][3-[2-fluoro-4-(trifluoromethyl)phenyl]-7-hydroxyquinolin-4-yl]methanone→(4-Fluorophenyl)[3-[2-fluoro-4-(trifluoromethyl)phenyl]-7-hydroxyquinolin-4-yl]methanone→4-[(R)-[4-(2,2-Diethoxyethoxy)phenyl](hydroxy)methyl]-3-[2-fluoro-4-(trifluoromethyl)phenyl]quinolin-7-ol→(5R)-5-[4-(2,2-Diethoxyethoxy)phenyl]-8-(trifluoromethyl)-5H-[1]benzopyrano[4,3-c]quinolin-2-ol
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 | 操作 |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 3-Methyl-1,2,4-thiadiazole-5-carbohydrazide Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | (R)-3-Methylpiperazin-2-one Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | (R)-4-(2,4-diMethoxybenzyl)-3-Methylpiperazin-2-one Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | 3-Methyl-piperazin-2-one Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | 5-bromo-3-methyl-1,2,4-thiadiazole Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | 3-Methyl-[1,2,4]thiadiazole-5-carboxylic acid ethyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。