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CAS 4334-88-7
4-(Ethoxycarbonyl)phenylboronic acid(4-(ethoxycarbonyl)phenyl)boronic acid
登记编号：(XI)91299-1-b、MOME-002、ETC-206-004
应用背景（按来源药适应症）
疟原虫感染青蒿琥酯/磷酸咯萘啶新型冠状病毒感染青蒿琥酯/磷酸咯萘啶恶性疟青蒿琥酯/磷酸咯萘啶疟原虫感染青蒿琥酯/盐酸甲氟喹恶性疟青蒿琥酯/盐酸甲氟喹疟原虫感染青蒿琥酯肠道肿瘤青蒿琥酯结肠癌青蒿琥酯宫颈上皮内瘤变青蒿琥酯HIV感染青蒿琥酯宫颈癌青蒿琥酯骨髓纤维化Momelotinib Dihydrochloride骨髓增生性疾病Momelotinib Dihydrochloride脾大Momelotinib Dihydrochloride贫血Momelotinib DihydrochlorideVEXAS综合征Momelotinib Dihydrochloride原发性血小板增多症Momelotinib Dihydrochloride结直肠癌Tinodasertib
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 青蒿琥酯/磷酸咯萘啶Artesunate/Pyronaridine Phosphate | Tier C · 观察 / 贸易 | - |
| 青蒿琥酯/盐酸甲氟喹Artesunate/Mefloquine Hydrochloride | Tier C · 观察 / 贸易 | - |
| 青蒿琥酯Artesunate | Tier C · 观察 / 贸易 | - |
| Momelotinib Dihydrochloride | Tier C · 观察 / 贸易 | - |
| Tinodasertib | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
1,4-Bis(trifluoromethyl)benzene→1,4-Dibromo-2,5-bis(trifluoromethyl)benzene→(4-Hydroxyphenyl)boronic acid→2(2),2(5)-Bis(trifluoromethyl)[1(1),2(1):2(4),3(1)-terphenyl]-1(4),3(4)-diol→1(3),1(5),3(3),3(5)-Tetrabromo-2(2),2(5)-bis(trifluoromethyl)[1(1),2(1):2(4),3(1)-terphenyl]-1(4),3(4)-diol→1(3),1(5),3(3),3(5)-Tetrabromo-1(4),3(4)-dimethoxy-2(2),2(5)-bis(trifluoromethyl)-1(1),2(1):2(4),3(1)-terphenyl→4-(Ethoxycarbonyl)phenylboronic acid→Ethyl 4-[5-[4-[3,5-bis(4-ethoxycarbonylphenyl)-4-methoxy-phenyl]-2,5-bis(trifluoromethyl)phenyl]-3-(4-ethoxycarbonylphenyl)-2-methoxy-phenyl]benzoate→4-[5-[4-[3,5-Bis(4-carboxyphenyl)-4-methoxy-phenyl]-2,5-bis(trifluoromethyl)phenyl]-3-(4-carboxyphenyl)-2-methoxy-phenyl]benzoic acid
1,4-Bis(trifluoromethyl)benzene→1,4-Dibromo-2,5-bis(trifluoromethyl)benzene→(4-Hydroxyphenyl)boronic acid→2(2),2(5)-Bis(trifluoromethyl)[1(1),2(1):2(4),3(1)-terphenyl]-1(4),3(4)-diol→1(3),1(5),3(3),3(5)-Tetrabromo-2(2),2(5)-bis(trifluoromethyl)[1(1),2(1):2(4),3(1)-terphenyl]-1(4),3(4)-diol→1(3),1(5),3(3),3(5)-Tetrabromo-1(4),3(4)-dimethoxy-2(2),2(5)-bis(trifluoromethyl)-1(1),2(1):2(4),3(1)-terphenyl→4-(Ethoxycarbonyl)phenylboronic acid→Ethyl 4-[5-[4-[3,5-bis(4-ethoxycarbonylphenyl)-4-methoxy-phenyl]-2,5-bis(trifluoromethyl)phenyl]-3-(4-ethoxycarbonylphenyl)-2-methoxy-phenyl]benzoate→4-[5-[4-[3,5-Bis(4-carboxyphenyl)-4-methoxy-phenyl]-2,5-bis(trifluoromethyl)phenyl]-3-(4-carboxyphenyl)-2-methoxy-phenyl]benzoic acid
1,4-Bis(trifluoromethyl)benzene→1,4-Dibromo-2,5-bis(trifluoromethyl)benzene→(4-Hydroxyphenyl)boronic acid→2(2),2(5)-Bis(trifluoromethyl)[1(1),2(1):2(4),3(1)-terphenyl]-1(4),3(4)-diol→1(3),1(5),3(3),3(5)-Tetrabromo-2(2),2(5)-bis(trifluoromethyl)[1(1),2(1):2(4),3(1)-terphenyl]-1(4),3(4)-diol→1(3),1(5),3(3),3(5)-Tetrabromo-1(4),3(4)-dimethoxy-2(2),2(5)-bis(trifluoromethyl)-1(1),2(1):2(4),3(1)-terphenyl→4-(Ethoxycarbonyl)phenylboronic acid→Ethyl 4-[5-[4-[3,5-bis(4-ethoxycarbonylphenyl)-4-methoxy-phenyl]-2,5-bis(trifluoromethyl)phenyl]-3-(4-ethoxycarbonylphenyl)-2-methoxy-phenyl]benzoate→4-[5-[4-[3,5-Bis(4-carboxyphenyl)-4-methoxy-phenyl]-2,5-bis(trifluoromethyl)phenyl]-3-(4-carboxyphenyl)-2-methoxy-phenyl]benzoic acid
4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-a]pyridin-3-yl)benzonitrile→6-bromo-3-iodoimidazo[1,2-a]pyridine→(4-cyanophenyl)boronic acid→4-(6-bromoimidazo[1,2-a]pyridin-3-yl)benzonitrile→(4-(ethoxycarbonyl)phenyl)boronic acid→ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)benzoate→4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)benzoic acid
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。