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CAS 56-06-4
2,4-Diamino-6-hydroxypyrimidine2,6-diaminopyrimidin-4(3H)-one
登记编号：Folic Acid-059、PEME-015
应用背景（按来源药适应症）
原发性高血压马来酸依那普利/叶酸巨幼红细胞性贫血叶酸叶酸缺乏叶酸神经管缺损叶酸贫血叶酸热潮红叶酸高同型半胱氨酸血症叶酸非小细胞肺癌培美曲塞二钠间皮组织肿瘤培美曲塞二钠胸膜孤立性纤维瘤培美曲塞二钠膀胱癌培美曲塞二钠尿路上皮癌培美曲塞二钠实体瘤培美曲塞二钠
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 马来酸依那普利/叶酸Enalapril Maleate/Folic Acid | Tier C · 观察 / 贸易 | - |
| 叶酸Folic Acid | Tier C · 观察 / 贸易 | - |
| 培美曲塞二钠Pemetrexed Disodium Hydrate | Tier B · 提前布局 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
(Methoxycarbonyl)acetonitrile→Guanidine sulfate→2,4-Diamino-6-hydroxypyrimidine→2,4-Diamino-6-hydroxy-5-nitrosopyrimidine→2,5,6-Triaminopyrimidin-4-ol→Sulfuric acid 2,5,6-triaminopyrimidin-4(1H)-one→2,5,6-Triaminopyrimidin-4-ol dihydrobromide→2,5,6-Triaminopyrimidin-4-one dihydrochloride→3-Bromo-2-oxopropanal oxime→1-Chloro-3-(hydroxyimino)propan-2-one→2-Amino-6-(bromomethyl)-4-pteridinol→2-Amino-6-(chloromethyl)-4-pteridinol→N-(4-Aminobenzoyl)-L-glutamic acid
(Methoxycarbonyl)acetonitrile→Guanidine sulfate→2,4-Diamino-6-hydroxypyrimidine→2,4-Diamino-6-hydroxy-5-nitrosopyrimidine→2,5,6-Triaminopyrimidin-4-ol→Sulfuric acid 2,5,6-triaminopyrimidin-4(1H)-one→2,5,6-Triaminopyrimidin-4-ol dihydrobromide→2,5,6-Triaminopyrimidin-4-one dihydrochloride→3-Bromo-2-oxopropanal oxime→1-Chloro-3-(hydroxyimino)propan-2-one→2-Amino-6-(bromomethyl)-4-pteridinol→2-Amino-6-(chloromethyl)-4-pteridinol→N-(4-Aminobenzoyl)-L-glutamic acid
methyl 4-bromobenzoate→but-3-yn-1-ol→methyl 4-(4-hydroxybut-1-yn-1-yl)benzoate→methyl 4-(4-hydroxybutyl)benzoate→methyl 4-(4-oxobutyl)benzoate→methyl 4-(3-bromo-4-oxobutyl)benzoate→2,6-diaminopyrimidin-4(3H)-one→methyl 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate→4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoic acid→diethyl (4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate compound with 4-methylbenzenesulfonamide (1:1)
dimethyl (4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate→2,6-diaminopyrimidin-4(3H)-one→4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoic acid→ethyl 4-(3-oxopropyl)benzoate→3-ethylbenzo[d]thiazol-3-ium bromide→ethyl 4-(4-hydroxy-3-oxobutyl)benzoate
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。