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CAS 95306-64-2
4-amino-5-methylpyridin-2(1H)-one4-Amino-5-methylpyridin-2(1H)-one
Codes: FINE-005, (V)90859-10-a, (VI)638294-1-a,(VI)638294-1-e, (VIII)638294-2-a, (I)638294-3-a,(I)638294-3-b, (I)638294-4-a, (V)638294-5-a, (IV)638294-6-a, (V)638294-7-a, (V)638294-9-a, (IV)638294-10-a,(IV)638294-10-b, (IV)638294-11-a +9 more
Application context (from source-drug indications)
Systolic heart failureFinerenoneDiastolic heart failureFinerenoneHeart failureFinerenoneChronic renal impairmentFinerenoneDiabetic nephropathyFinerenoneType 2 diabetesFinerenone
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Finerenone | Tier C — Watch / trade | 2030 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
tert-butyl (E)-3-(4-cyano-2-methoxyphenyl)acrylate→4-formyl-3-methoxybenzonitrile→2-cyanoethyl 3-oxobutanoate→2-cyanoethyl (Z)-2-(4-cyano-2-methoxybenzylidene)-3-oxobutanoate→4-amino-5-methylpyridin-2(1H)-one→2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate→2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylate→4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid→4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
2-Chloro-5-methylpyridine→2-Chloro-5-methyl-1-oxidopyridin-1-ium→2-Chloro-5-methyl-4-nitro-1-oxidopyridin-1-ium→2-Chloro-5-methylpyridin-4-amine→4-Amino-5-methylpyridin-2(1H)-one→1,3-Dichloro-1,3-propanedione→Ethyl cyanide→6-Chloro-5-methylpyridine-2,4-diol hydrogen chloride (1/1)→2,4-Dihydroxy-5-methylpyridine→2-Methoxy-5-methylpyridin-4-amine
2,2-Dimethyl-6-methyl-1,3-dioxin-4-one→1-Cyano-2-hydroxyethane→2-Cyanoethyl 3-oxobutanoate→2-Methoxy-4-cyanobenzaldehyde→2-Cyanoethyl (2Z)-2-[(4-cyano-2-methoxyphenyl)methylene]-3-oxobutanoate→4-Amino-5-methylpyridin-2(1H)-one→2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate→(Diethoxymethoxy)ethane→1,1,1-Triethoxyethane→2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylate→4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid→(±)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide→4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,6-naphthyridine-3-carboxamide
2-Methoxy-4-cyanobenzaldehyde→4-Amino-5-methylpyridin-2(1H)-one→1,1,1-Triethoxyethane→4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid→2,8-Dimethyl-5-oxo-5,6-dihydro-1,6-naphthyridine-3-carbonitrile→4-(4-Cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carbonitrile→1-Cyano-2-propanone→4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carbonitrile→2-Methylidene-3-oxobutanenitrile→2-Methoxy-4-cyanobromobenzene
4-Bromo-2-hydroxybenzoic acid→2-Methoxy-4-bromobenzoic acid methyl ester→4-Bromo-2-methoxybenzaldehyde→2-Methoxy-4-cyanobenzaldehyde→3-Oxobutanamide→(2E)-2-[(4-Cyano-2-methoxyphenyl)methylidene]-3-oxobutanamide→(2Z)-2-[(4-Cyano-2-methoxyphenyl)methylidene]-3-oxobutanamide→4-Amino-5-methylpyridin-2(1H)-one→4-(4-Cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxamide→1,1,1-Triethoxyethane→(±)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide→2,4-Dihydroxy-5-methylpyridine→1-Phenylmethylamine→4-(Benzylamino)-5-methylpyridin-2(1H)-one
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 4-AMino-5-Methylpyridin-2-ol Pharmaceutical Intermediates | On request | On request | On request | — |
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