核苷 & 核酸
核苷（酸）类似物 API、碱基 / 核糖片段中间体与专利悬崖核苷类品种
专利悬崖品种38
多替拉韦/拉米夫定/艾酚福韦Tier C
Dolutegravir/Lamivudine/Tenofovir Alafenamide
拉米夫定/富马酸替诺福韦二吡呋酯Tier C
Lamivudine/Tenofovir Disoproxil Fumarate
比克恩丙诺Tier B
Bictegravir/Emtricitabine/Tenofovir Alafenamide Fumarate
依非韦伦/拉米夫定/富马酸替诺福韦二吡呋酯Tier C
Efavirenz/Lamivudine/Tenofovir Disoproxil Fumarate
富马酸磷丙替诺福韦Tier B
Tenofovir Alafenamide Fumarate
Grazoprevir HydrateTier C
Grazoprevir Hydrate
艾尔巴韦Tier C
Elbasvir
索磷布韦/维帕他韦Tier B
Sofosbuvir/Velpatasvir
恩曲他滨/富马酸磷丙替诺福韦Tier B
Emtricitabine/Tenofovir Alafenamide Fumarate
帕利普韦/奥比他韦/利托那韦Tier C
Paritaprevir/Ombitasvir/Ritonavir
西美瑞韦钠Tier B
Simeprevir Sodium
恩曲他滨/盐酸利匹韦林/富马酸替诺福韦二吡呋酯Tier B
Emtricitabine/Rilpivirine Hydrochloride/Tenofovir Disoproxil Fumarate
地西他滨Tier C
Decitabine
拉米夫定Tier C
Lamivudine
磷酸替诺福韦二吡呋酯Tier C
Tenofovir disoproxil phosphate
恩曲他滨Tier C
Emtricitabine
索磷布韦Tier B
Sofosbuvir
甲磺酸普雷福韦Tier C
Pradefovir Mesylate
莫诺拉韦Tier B
Molnupiravir
Daclatasvir dihydrochloride/Asunaprevir/Beclabuvir hydrochlorideTier C
Daclatasvir dihydrochloride/Asunaprevir/Beclabuvir hydrochloride
硫酸阿巴卡韦/拉米夫定Tier B
Abacavir Sulfate/Lamivudine
恩曲他滨/富马酸替诺福韦二吡呋酯Tier B
Emtricitabine/Tenofovir Disoproxil Fumarate
阿扎胞苷Tier C
Azacitidine
阿德福韦酯Tier C
Adefovir Dipivoxil
硫酸阿巴卡韦/拉米夫定/齐多夫定Tier C
Abacavir Sulfate/Lamivudine/Zidovudine
硫酸阿巴卡韦Tier C
Abacavir Sulfate
更昔洛韦眼用凝胶 (Laboratoires Thea)Tier C
Ganciclovir ophthalmic gel (Laboratoires Thea)
盐酸吉西他滨/多西他赛Tier C
Gemcitabine Hydrochloride/Docetaxel
Antisense Oligonucleotides (EveryONE Medicines)Tier C
Antisense Oligonucleotides (EveryONE Medicines)
普瑞拉滨Tier C
Pracytarabine
ValganciclovirTier C
Valganciclovir
Lenacapavir/IslatravirTier C
Lenacapavir/Islatravir
Gemcitabine controlled release (TARIS Biomedical)Tier C
Gemcitabine controlled release (TARIS Biomedical)
地西他滨/四氢尿苷 (EpiDestiny/Novo Nordisk)Tier C
Decitabine/Tetrahydrouridine (EpiDestiny/Novo Nordisk)
阿扎胞苷 ((韩国保宁制药)Tier C
Azacitidine (Boryung Pharmaceutical)
洛匹那韦/利托那韦/齐多夫定/拉米夫定Tier C
Lopinavir/Ritonavir/Lamivudine/Zidovudine
Fosifloxuridine nafalbenamideTier C
Fosifloxuridine nafalbenamide
Guadecitabine SodiumTier C
Guadecitabine Sodium
原料药 API3
中间体目录4
| 6-Chloro-3-methyluracil | CAS 4318-56-3 |
| 6-Chlorouracil | CAS 4270-27-3 |
| 2'-Deoxy-2'-fluoro-2'- Methyl-N-(phenylcarbonyl) cytidine | CAS 817204-32-3 |
| 2'-deoxy-2'-fluoro-2'-C-methyluridine | CAS 863329-66-2 |