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CAS 3536-96-7
Chlorido(ethenyl)magnesium
登记编号：(IX)101438-57-a、Atorvastatin-094、Chlorphenamine Maleate-008、(IIa)955428-2-a、Astaxanthin-045
应用背景（按来源药适应症）
乳腺癌Paclitaxel/Encequidar mesylate腺癌Paclitaxel/Encequidar mesylate血管肉瘤Paclitaxel/Encequidar mesylate实体瘤Paclitaxel/Encequidar mesylate心脏和血管疾病阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利高血压阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利高脂血症阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利心脏病阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利鼻塞氢溴酸右美沙芬/马来酸氯苯那敏/氯化铵打喷嚏氢溴酸右美沙芬/马来酸氯苯那敏/氯化铵咳嗽氢溴酸右美沙芬/马来酸氯苯那敏/氯化铵高脂血症阿托伐他汀锶蛛网膜下腔出血阿托伐他汀锶高血压阿托伐他汀锶感冒对乙酰氨基酚/马来酸氯苯那敏/盐酸甲基麻黄碱/愈创木酚磺酸钾/咖啡因超敏反应马来酸氯苯那敏季节性过敏性鼻炎马来酸氯苯那敏皮炎马来酸氯苯那敏荨麻疹马来酸氯苯那敏瘙痒症马来酸氯苯那敏药疹马来酸氯苯那敏胰腺癌紫杉醇非小细胞肺癌紫杉醇霍奇金病紫杉醇精原细胞瘤紫杉醇卵巢癌紫杉醇乳腺癌紫杉醇外周T细胞淋巴瘤戈利昔替尼EB病毒感染戈利昔替尼病毒感染戈利昔替尼组织细胞增生戈利昔替尼噬血细胞性淋巴组织细胞增多症戈利昔替尼间质性肺疾病戈利昔替尼营养失调虾青素膝关节炎虾青素糖尿病神经病变虾青素中风虾青素
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| Paclitaxel/Encequidar mesylate | Tier C · 观察 / 贸易 | - |
| 阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利Atorvastatin/Hydrochlorothiazide/Aspirin/Enalapril | Tier C · 观察 / 贸易 | - |
| 氢溴酸右美沙芬/马来酸氯苯那敏/氯化铵Dextromethorphan Hydrobromide/Chlorphenamine Maleate/Ammonium chloride | Tier C · 观察 / 贸易 | - |
| 阿托伐他汀锶Atorvastatin strontium | Tier C · 观察 / 贸易 | - |
| 对乙酰氨基酚/马来酸氯苯那敏/盐酸甲基麻黄碱/愈创木酚磺酸钾/咖啡因Acetaminophen/Chlorphenamine Maleate/Methylephedrine Hydrochloride/Sulfogaiacol/Caffeine | Tier C · 观察 / 贸易 | - |
| 马来酸氯苯那敏Chlorphenamine Maleate | Tier C · 观察 / 贸易 | - |
| 紫杉醇Paclitaxel | Tier B · 提前布局 | - |
| 戈利昔替尼Golidocitinib | Tier C · 观察 / 贸易 | - |
| 虾青素Astaxanthin | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
1-Methoxy-3-methylbenzene→1-Methoxy-5-methyl-1,4-cyclohexadiene→7-Methyl-1,4-dioxaspiro[4.5]dec-7-ene→3-Methyl-2-cyclohexen-1-one→Chlorido(ethenyl)magnesium→(±)-7-Methyl-1,4-dioxaspiro[4.5]decane-7,8-diol→(-)-(7R,8S)-7-Methyl-1,4-dioxaspiro[4.5]decane-7,8-diol→(7R,8S)-8-(Benzyloxy)-7-methyl-1,4-dioxaspiro[4.5]decan-7-ol→(4S)-4-(Benzyloxy)-3-methylcyclohex-2-en-1-one→[[(3S,4S)-4-(Benzyloxy)-3-ethenyl-3-methylcyclohex-1-en-1-yl]oxy](trimethyl)silane→(2R,3S,4S)-4-(Benzyloxy)-2-(hydroxymethyl)-3-methyl-3-vinylcyclohexanone→(2S,3S,4S)-4-(Benzyloxy)-3-ethenyl-2-(hydroxymethyl)-3-methylcyclohexanone
(3R)-3-Hydroxyhex-5-enenitrile→Chlorido(ethenyl)magnesium→(2R)-1-Chloropent-4-en-2-ol→(3R)-3-[(Trimethylsilyl)oxy]hex-5-enenitrile→tert-Butyl (5R)-5-hydroxy-3-oxooct-7-enoate→tert-Butyl [(4R,6R)-6-[(2E)-2-(hydroxyimino)ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate→tert-Butyl (3R,5R)-3,5-dihydroxyoct-7-enoate→tert-Butyl [(4R,6R)-6-allyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate→tert-Butyl [(4R,6S)-2,2-dimethyl-6-(2-oxoethyl)-1,3-dioxan-4-yl]acetate→Hydroxylamine hydrochloric acid→(4R)-2,2-Dimethyl-6beta-(2-hydroxyethyl)-1,3-dioxane-4beta-acetic acid tert-butyl ester→tert-Butyl [(4R,6R)-6-[2-[(methanesulfonyl)oxy]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate→tert-Butyl [(4R,6R)-6-(2-azidoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate→(2R)-2-(Chloromethyl)oxirane→1-Methoxy-1-methylethyl methyl ether→1,1-Dimethylethyl monobromoacetate→(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester→1,1-Dimethylethyl acetate→Methyl (3R)-3-hydroxyhex-5-enoate
(2R)-2-Aminobutanedioic acid→(2R)-2-Chlorobutanedioic acid→(2R)-2-Chlorobutane-1,4-diol→2-[(2S)-Oxiran-2-yl]ethan-1-ol→(4S,6S)-4-[2-(Benzyloxy)ethyl]-6-(bromomethyl)-1,3-dioxan-2-one→(2S)-2-[2-(Benzyloxy)ethyl]oxirane→(3R)-1-(Benzyloxy)hex-5-en-3-ol→(3R)-1-(Benzyloxy)hex-5-en-3-yl tert-butyl carbonate→(4S,6S)-4-[2-(Benzyloxy)ethyl]-6-(bromomethyl)-2,2-dimethyl-1,3-dioxane→6-O-Acetyl-1-O-benzyl-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexitol→1-O-Benzyl-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexitol→6-O-Benzyl-3,5-dideoxy-2,4-O-(1-methylethylidene)-L-erythro-hexose→2-[(4R,6S)-6-[2-(Benzyloxy)ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]ethanamine→(6xi)-1-O-Benzyl-2,4,7-trideoxy-3,5-O-(1-methylethylidene)-7-nitro-D-erythro-heptitol→(6xi)-6-O-Acetyl-1-O-benzyl-2,4,7-trideoxy-3,5-O-(1-methylethylidene)-7-nitro-D-erythro-heptitol→(4S,6R)-4-[2-(Benzyloxy)ethyl]-2,2-dimethyl-6-(2-nitroethyl)-1,3-dioxane→2-Propanone→Nitrocarbol→Chlorido(ethenyl)magnesium
N-Methoxy-N-methylpyridine-2-carboxamide→Chlorido(ethenyl)magnesium→Dimethylamine→3-(Dimethylamino)-1-(pyridin-2-yl)propan-1-one→N,N-Dimethyl-2-([1,2,3]triazolo[1,5-a]pyridin-3-yl)ethan-1-amine→(4-Chlorophenyl)boranediol→1-(p-Chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane
(3R)-3-Hydroxyhex-5-enenitrile→Chlorido(ethenyl)magnesium→(2R)-1-Chloropent-4-en-2-ol→(3R)-3-[(Trimethylsilyl)oxy]hex-5-enenitrile→tert-Butyl (5R)-5-hydroxy-3-oxooct-7-enoate→tert-Butyl [(4R,6R)-6-[(2E)-2-(hydroxyimino)ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate→tert-Butyl (3R,5R)-3,5-dihydroxyoct-7-enoate→tert-Butyl [(4R,6R)-6-allyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate→tert-Butyl [(4R,6S)-2,2-dimethyl-6-(2-oxoethyl)-1,3-dioxan-4-yl]acetate→Hydroxylamine hydrochloric acid→(4R)-2,2-Dimethyl-6beta-(2-hydroxyethyl)-1,3-dioxane-4beta-acetic acid tert-butyl ester→tert-Butyl [(4R,6R)-6-[2-[(methanesulfonyl)oxy]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate→tert-Butyl [(4R,6R)-6-(2-azidoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate→(2R)-2-(Chloromethyl)oxirane→1-Methoxy-1-methylethyl methyl ether→1,1-Dimethylethyl monobromoacetate→(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester→1,1-Dimethylethyl acetate→Methyl (3R)-3-hydroxyhex-5-enoate
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。