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CAS 753-90-2
2,2,2-trifluoroethan-1-amine2-Amino-1,1,1-trifluoroethane
登记编号：ABT-494-003、(XVIIb)700647-1-b
应用背景（按来源药适应症）
斑秃乌帕替尼巨细胞性动脉炎乌帕替尼强直性脊柱炎乌帕替尼椎关节炎乌帕替尼克罗恩病乌帕替尼非放射学性轴性脊柱关节炎乌帕替尼蠕形螨性睑缘炎洛替拉纳螨虫感染洛替拉纳莱姆病洛替拉纳酒渣鼻洛替拉纳睑板腺功能障碍洛替拉纳
来源药（使用该中间体的合成路线）
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
benzyl (3S,4R)-3-ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)pyrrolidine-1-carboxylate→8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine→2,2,2-trifluoroethan-1-amine→(3S,4R)-3-ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
2-Amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride→2,5-Dioxo-3-oxazolidinecarboxylic acid 1,1-dimethylethyl ester→2-(Benzyloxycarbonylamino)acetic acid→2-((tert-Butoxycarbonyl)amino)acetic acid→2-Amino-1,1,1-trifluoroethane hydrochloride→2-Amino-1,1,1-trifluoroethane→Benzyl [2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]carbamate→[(2,2,2-Trifluoroethylcarbamoyl)methyl]carbamic acid tert-butyl ester→2-Chloranylethanoyl chloride→2-Chloro-N-(2,2,2-trifluoroethyl)acetamide→(N-Benzylaminomethyl)benzene→2-(Dibenzylamino)-N-(2,2,2-trifluoroethyl)acetamide
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 | 操作 |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 2-bromo-3-methyl-5-acetylthiophene Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | methyl 5-acetyl-3-methylthiophene-2-carboxylate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | 5-acetyl-3-methyl-2-Thiophenecarboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | (3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic acid ethyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | N-Tosyl-5-bromo-4,7-diazaindole Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | 8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | 5-Bromo-4,7-diazaindole Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。