品名 / CAS	纯度 / 杂质谱（脱敏）	合成路线（脱敏）	产能	资质	包装 / 冷链	起订 / 价格带	操作
Orforglipron INT-1｜5-溴-4-氟-1-甲基吲唑 CAS 1784678-61-0 · GLP-1（代谢）对应药物：orforglipron 高保密	≥99.0% 单杂 ≤0.10%（脱敏）	吲唑环构建 + N-甲基化（脱敏简述）	2,000 kg/年	US DMF	5 kg / 25 kg 桶	5 kg US$ 1,850-2,600 / kg	Unibest Nantong cGMP Site
Orforglipron INT-2｜(S)-4-甲基-1,3,2-二氧硫杂环戊烷-2,2-二氧化物 CAS 174953-30-1 · GLP-1（代谢）对应药物：orforglipron 高保密	≥99.0% 手性纯度 ≥99.5% ee（脱敏）	手性二醇环硫酸酯化（脱敏简述）	1,500 kg/年		5 kg 桶	5 kg US$ 980-1,450 / kg	Unibest Nantong cGMP Site
Orforglipron INT-3｜(4-氟-3,5-二甲基苯基)肼盐酸盐 CAS 2212021-40-2 · GLP-1（代谢）对应药物：orforglipron CDA 后可看	≥98.5% 单杂 ≤0.20%（脱敏）	重氮化还原（脱敏简述）	3,000 kg/年		25 kg 桶	10 kg US$ 560-820 / kg	Unibest Taizhou GMP-like Site
Orforglipron INT-4｜(S)-3-氨基丁腈盐酸盐 CAS 1073666-54-2 · GLP-1（代谢）对应药物：orforglipron CDA 后可看	≥99.0% 手性纯度 ≥99.5% ee（脱敏）	不对称合成 + 成盐（脱敏简述）	2,200 kg/年		25 kg 桶	10 kg US$ 640-950 / kg	Unibest Taizhou GMP-like Site

官方中间体全量目录含 CAS 号 · 按对应药物聚合

共 58 个中间体 · 覆盖 255 个药物

第 1 / 1 页

中间体名称	CAS 号	对应药物
(R)-2-[[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-y]methyl]-4-fluorobenzonitrile	865759-25-7	Alogliptin/ Trelagliptin
(R)-3-(Boc-Amino)piperidine	309956-78-3	Alogliptin/ Trelagliptin
(R)-3-aminopiperidine dihydrochloride	334618-23-4	Alogliptin/ Trelagliptin
2-[(6-Chloro-3,4-dihydro-3-methy1-2,4-dioxo-1(2H)-pyrimidinyl)methyl]benzonitrile	865758-96-9	Alogliptin/ Trelagliptin
2-Cyano-5-fluorobenzyl bromide	421552-12-7	Alogliptin/ Trelagliptin
2-Cyanobenzyl bromide	22115-41-9	Alogliptin/ Trelagliptin
6-Chloro-3-methyluracil	4318-56-3	Alogliptin/ Trelagliptin
6-Chlorouracil	4270-27-3	Alogliptin/ Trelagliptin
(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]pheny!]D-glucitol tetraacetate	461432-25-7	Dapagliflozin
(2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol	714269-57-5	Dapagliflozin
(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone	461432-22-4	Dapagliflozin
1-Chloro-2-(4-ethoxybenzyl)-4-iodobenzene	1103738-29-9	Dapagliflozin
2,3,4,6-Tetrakis-0-trimethylsilyl-D-gluconolactone	32384-65-9	Dapagliflozin
4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether	461432-23-5	Dapagliflozin
5-Bromo-2-chlorobenzoic acid	21739-92-4	Dapagliflozin
(1R,3aR,7aR)-1-((R)-6-hydroxy-6-Methylheptan-2-yl)-7a-Methylhexahydro-1H-inden-4(2H)-one	70550-73-1	Eldecalcitol
4H-Inden-4-one, 1-[1,5-dimethyl-5-[(triethylsilyl)oxy]hexyl]octahydro-7a-methyl-, [1R-[1α(R*),3aβ,7aα]]-	144848-24-8	Eldecalcitol
de-A,B-25-hydroxycholestan-8β-ol	66774-84-3	Eldecalcitol
Eldecalcitol interMediates	200636-42-6	Eldecalcitol
Phosphine oxide, [(2Z)-2-[(3R,4R,5R)-2-methylene-3,5-bis[(triethylsilyl)oxy]-4-[3-[(triethylsilyl)oxy]propoxy]cyclohexylidene]ethyl]diphenyl-	2189732-17-8	Eldecalcitol
Phosphine oxide, [(2Z)-2-[(3R,4R,5R)-3,5-bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-4-[3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]propoxy]-2-Methylenecyclohexylidene]ethyl]diphenyl-	200636-54-0	Eldecalcitol
(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl] -D-glucitol tetraacetate	915095-99-7	Empagliflozin
(5-Bromo-2-chlorophenyl)(4-fluorophenyl)methanone	915095-85-1	Empagliflozin
(5-Bromo-2-chlorophenyl)[4-[[(3S)-tetrahydro-3-furanylloxy]phenyllmethanone	915095-84-0	Empagliflozin
(S)-(+)-3-Hydroxytetrahydrofuran	86087-23-2	Empagliflozin
(S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran	915095-94-2	Empagliflozin
(S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran	915095-89-5	Empagliflozin
2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone	32384-65-9	Empagliflozin
4-((5-Bromo-2-chlorophenyl)methyl)phenol	864070-18-8	Empagliflozin
[(3R)-1-[7-(2-Butynyl)-2,3,6,7-tetrahydro-3-methy1-1-[(4-methy1-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yll-3-piperidinyllcarbamicacid 1,1-dimethylethyl ester	668273-75-4	Linagliptin
2-(Chloromethyl)-4-methylquinazoline	109113-72-6	Linagliptin
3-Methylxanthine	1076-22-8	Linagliptin
8-Bromo-3-methyl-3,9-dihydro-1H-purine-2,6-dione	93703-24-3	Linagliptin
8-Bromo-7-(but-2-yn-1-yl)-3-methy1-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione	853029-57-9	Linagliptin
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione	666816-98-4	Linagliptin
(2S)-tert-Butyl 3-cyano-2-methyl-4-oxopiperidine-1-carboxylate	2212021-56-0	Orforglipron
(4-Fluoro-3,5-dimethylphenyl)hydrazine hydrochloride	2212021-40-2	Orforglipron
(E)-3-(2-(methyl(phenyl)carbamoyl)-1H-indol-5-yl)acrylic acid	3047292-97-4	Orforglipron
(R,E)-N-methyl-5-(3-oxo-3-(2-oxo-4-phenyloxazolidin-3-yl)prop-1-en-1-yl)-N-phenyl-1H-indole-2-carboxamide	3047293-00-2	Orforglipron
(R)-4-Benzyl-2-oxazolidinone	102029-44-7	Orforglipron
(S)-3-Aminobutanenitrile Hydrochloride	1073666-54-2	Orforglipron
(S)-5-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide	2212021-79-7	Orforglipron
1-(4-fluoro-1-methyl-1H-indazole-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-yl)-1,3-dihydro-2H-imidazole-2-one hydrochloride	3036782-75-6	Orforglipron
1-(cyanomethyl)-5-[(4S)-2,2-dimethyloxan-4-yl]-N-methyl-N-phenylindole-2-carboxamide	2212021-80-0	Orforglipron
1,3,2-Dioxathiolane, 4-Methyl-, 2,2-dioxide, (4R)-	1006381-03-8	Orforglipron
2H-Imidazol-2-one, 1-[(4S)-2-(4-fluoro-3,5- dimethylpheny1)-4,5,6,7-2H-Imidazol-2-one, 1-[(4S)-2- (4-fluoro-3,5-dimethylpheny1)-4,5,6,7-1H- indazol-5- yl)- 1,3-dihydro-	2212022-56-3	Orforglipron
3-(3-(4-fluoro-1-methyl-1H-indazole-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2-(4-fluoro-3,5-dimethylphenyl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester	3036782-74-5	Orforglipron
5-[(S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl]-1-[(1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl]-1H-indole-2-carboxylic Acid	2212021-83-3	Orforglipron
5-Bromo-2-fluoro-m-xylene	99725-44-7	Orforglipron
5-Bromo-4-fluoro-1-methyl-1H-indazole	1784678-61-0	Orforglipron
5-bromo-N-methyl-N-phenyl-1H-indole-2-carboxamide	2860499-50-7	Orforglipron
5-Bromoindole-2-carboxylic acid	7254-19-5	Orforglipron
5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 3-(2,3-dihydro-2-oxo-1H-imidazol-1-yl)-2-(4-fluoro-3,5-dimethylphenyl)-2,4,6,7-tetrahydro-4-methyl-, 1,1-dimethylethyl ester, (4S)-	2212021-61-7	Orforglipron
H-Indole-2-carboxamide, 1-[(1S,2S)-1-cyano-2-methylcyclopropyl]-N-methyl-N-phenyl-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-	2212021-81-1	Orforglipron
N-Boc-L-Alaninol	79069-13-9	Orforglipron
tert-buty1 (S)-3-amino-2-(4- fluoro-3,5- dimethylpheny1)-4- methyl-2,4,6,7-tetrahydro-5H-pyrazoloB ,3-c ]pyridine-5-carboxylate	2212021-59-3	Orforglipron
tert-butyl 2-(4-fluoro-3,5-dimethylphenyl)-3-(2-oxo-1H-imidazol-3-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxylate	2212022-03-0	Orforglipron
tert-butyl 3-amino-2-(4-fluoro-3,5-dimethylphenyl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxylate	2212021-41-3	Orforglipron