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CAS 100-46-9
phenylmethanamine1-Phenylmethylamine
登记编号：LACO-006、(XIII)638294-2-a、(IX)638294-13-a、(IV)101438-34-a、(II)109067-9-a、VARE-017、L-Demethyl phencynonate hydrochloride-001
应用背景（按来源药适应症）
强直阵挛性癫痫拉考沙胺癫痫拉考沙胺癫痫部分性发作拉考沙胺癫痫发作拉考沙胺收缩性心力衰竭非奈利酮舒张期心力衰竭非奈利酮心脏衰竭非奈利酮慢性肾功能不全非奈利酮糖尿病肾病非奈利酮二型糖尿病非奈利酮乳腺癌Paclitaxel/Encequidar mesylate腺癌Paclitaxel/Encequidar mesylate血管肉瘤Paclitaxel/Encequidar mesylate实体瘤Paclitaxel/Encequidar mesylate高血压Olmesartan Medoxomil/Amlodipine orotate原发性高血压缬沙坦/氨氯地平乳清酸盐尼古丁依赖酒石酸伐尼克兰吸烟戒断酒石酸伐尼克兰戒烟酒石酸伐尼克兰减少吸烟酒石酸伐尼克兰大麻依赖酒石酸伐尼克兰雾化酒石酸伐尼克兰变异型心绞痛氨氯地平乳清酸盐高血压氨氯地平乳清酸盐缺血性心脏病氨氯地平乳清酸盐稳定型心绞痛氨氯地平乳清酸盐胰腺癌紫杉醇非小细胞肺癌紫杉醇霍奇金病紫杉醇精原细胞瘤紫杉醇卵巢癌紫杉醇乳腺癌紫杉醇高血压樟脑磺酸氨氯地平
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 拉考沙胺Lacosamide | Tier B · 提前布局 | 2028 |
| 非奈利酮Finerenone | Tier C · 观察 / 贸易 | 2030 |
| Paclitaxel/Encequidar mesylate | Tier C · 观察 / 贸易 | - |
| Olmesartan Medoxomil/Amlodipine orotate | Tier C · 观察 / 贸易 | - |
| 缬沙坦/氨氯地平乳清酸盐Valsartan/Amlodipine Orotate | Tier C · 观察 / 贸易 | - |
| 酒石酸伐尼克兰Varenicline Tartrate | Tier B · 提前布局 | - |
| 氨氯地平乳清酸盐Amlodipine Orotate | Tier C · 观察 / 贸易 | - |
| 紫杉醇Paclitaxel | Tier B · 提前布局 | - |
| 樟脑磺酸氨氯地平Amlodipine Camsylate | Tier C · 观察 / 贸易 | - |
| 左旋盐酸去甲基苯环壬酯L-Demethyl Phencynonate Hydrochloride | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
phenylmethanamine→N-acetyl-O-methyl-D-serine→methyl D-serinate→diethoxytriphenyl-l5-phosphane→ethyl (R)-aziridine-2-carboxylate→methyl (R)-aziridine-2-carboxylate→ethyl (R)-1-acetylaziridine-2-carboxylate→methyl (R)-1-acetylaziridine-2-carboxylate→ethyl N-acetyl-O-methyl-D-serinate→methyl N-acetyl-O-methyl-D-serinate→4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride→triphenylphosphane→sodium ethanolate
4-Bromo-2-hydroxybenzoic acid→2-Methoxy-4-bromobenzoic acid methyl ester→4-Bromo-2-methoxybenzaldehyde→2-Methoxy-4-cyanobenzaldehyde→3-Oxobutanamide→(2E)-2-[(4-Cyano-2-methoxyphenyl)methylidene]-3-oxobutanamide→(2Z)-2-[(4-Cyano-2-methoxyphenyl)methylidene]-3-oxobutanamide→4-Amino-5-methylpyridin-2(1H)-one→4-(4-Cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxamide→1,1,1-Triethoxyethane→(±)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide→2,4-Dihydroxy-5-methylpyridine→1-Phenylmethylamine→4-(Benzylamino)-5-methylpyridin-2(1H)-one
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 | 操作 |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 4-Bromo-2-methoxybenzaldehyde Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | 4-formyl-3-methoxybenzonitrile Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | 4-AMino-5-Methylpyridin-2-ol Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | 2-chloro-5-methylpyridin-4-amine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | 2-Cyanoethyl 3-oxobutanoate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | 1,4-DIHYDRO-1,4-METHANONAPHTHALENE Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | 2,3,4,5-TETRAHYDRO-1H-1,5-METHANO-3-BENZAZEPINE HYDROCHLORIDE Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Qualified Partner — East China API Works | 2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。