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CAS 532-24-1
8-Methyl-8-azabicyclo[3.2.1]octan-3-one8-methyl-8-azabicyclo[3.2.1]octan-3-one
登记编号：Ioflupane (123I)-006、BPN-13661-001
应用背景（按来源药适应症）
路易氏体型失智症Ioflupane (123I)诊断剂Ioflupane (123I)帕金森综合征Ioflupane (123I)阿尔茨海默病Ioflupane (123I)帕金森病Ioflupane (123I)痴呆Ioflupane (123I)药物中毒ORC-13661听力损失ORC-13661
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| Ioflupane (123I) | Tier C · 观察 / 贸易 | - |
| ORC-13661 | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
8-Methyl-8-azabicyclo[3.2.1]octan-3-one→Carbonicaciddimethyldiester→Hydroxymethane→Methyl8-methyl-3-oxo-8-azabicyclo[3.2.1]octane-2-carboxylate→Methyl3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate→Methyl8-methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate→1,4-Dibromobenzene→(±)-Methyl(1R*,2S*,3S*,5S*)-3-(4-bromophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate→(±)-Methyl(1R*,2S*,3S*,5S*)-3-(4-bromophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate→1-Bromo-3-fluoropropane→Methyl(1R,2S,3S,5S)-3-(4-bromophenyl)-8-(3-fluoropropyl)-8-azabicyclo[3.2.1]octane-2-carboxylate→Methyl(1R,2S,3S,5S)-8-(3-fluoropropyl)-3-[4-(trimethylstannyl)phenyl]-8-azabicyclo[3.2.1]octane-2-carboxylate
(4R,7S)-2-(3-(4-chlorophenyl)ureido)-9-methyl-5,6,7,8-tetrahydro-4H-4,7-epiminocyclohepta[b]thiophene-3-carboxamide hydrochloride→8-methyl-8-azabicyclo[3.2.1]octan-3-one→2-cyanoacetamide→2-amino-9-methyl-5,6,7,8-tetrahydro-4H-4,7-epiminocyclohepta[b]thiophene-3-carboxamide→1-chloro-4-isocyanatobenzene→2-(3-(4-chlorophenyl)ureido)-9-methyl-5,6,7,8-tetrahydro-4H-4,7-epiminocyclohepta[b]thiophene-3-carboxamide→(4R,7S)-2-(3-(4-chlorophenyl)ureido)-9-methyl-5,6,7,8-tetrahydro-4H-4,7-epiminocyclohepta[b]thiophene-3-carboxamide
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本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。