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CAS 5750-76-5
2,4,5-Trichloropyrimidine
登记编号：(XIX)909096-1-b、(XIX)805433-1-b、(XIV)919110-1-a
应用背景（按来源药适应症）
非小细胞肺癌伊鲁阿克特发性肺纤维化那米司特间质性肺疾病那米司特肺纤维化那米司特肌炎那米司特系统性硬皮病那米司特肌病那米司特非小细胞肺癌地罗阿克
来源药（使用该中间体的合成路线）
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
5-Chloro-2-(piperidin-4-yl)pyrimidine hydrogen chloride→4-Methylbenzene-1-sulfonic acid 5-chloro-2-(piperidin-4-yl)pyrimidine→5-Chloro-2-(piperidin-4-yl)pyrimidine sulfate→4-(5-Chloropyrimidin-2-yl)piperidin-1-ium hexafluoridophosphate(1-)→2,4,5-Trichloropyrimidine→4-Piperidinecarbonitrile→Methyl piperidine-4-carboximidate hydrogen chloride→Piperidine-4-carboximidamide→Piperidine-4-carboximidamide hydrogen chloride→2-Chloro-1,3-bis(dimentylamino)trimethinium hexafluorophosphate→2,5-Dichloropyrimidine→5-Chloro-2-iodopyrimidine→(1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester→Boc-4-(5-chloropyrimidin-2-yl)-3,6-dihydropyridine→Boc-4-(5-chloropyrimidin-2-yl)piperidine
2-Hydroxy-5-methylanisole→2-Methoxy-4-methyl-6-nitrophenol→5-Methyl-3-nitrobenzene-1,2-diol→1,2-Dibromoethane→7-Methyl-5-nitro-2,3-dihydro-1,4-benzodioxine→6-Bromo-7-methyl-5-nitro-2,3-dihydro-1,4-benzodioxine→6-Bromo-7-methyl-2,3-dihydro-1,4-benzodioxin-5-amine→6-Bromo-8-iodo-7-methyl-2,3-dihydro-1,4-benzodioxin-5-amine→(1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester→tert-Butyl 4-(8-amino-7-bromo-6-methyl-2,3-dihydro-1,4-benzodioxin-5-yl)-3,6-dihydropyridine-1(2H)-carboxylate→tert-Butyl 4-(8-amino-6-methyl-2,3-dihydro-1,4-benzodioxin-5-yl)piperidine-1-carboxylate→2,5-Dichloro-N-(2-((1-methylethyl)sulfonyl)phenyl)-4-pyrimidinamine→1-Amino-2-(isopropylsulphonyl)benzene→2,4,5-Trichloropyrimidine→tert-Butyl 4-(8-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-6-methyl-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperidine-1-carboxylate
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