← 返回专利悬崖列表
CAS 286961-14-6
tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxylateN-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester(1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester
登记编号：Dalpiciclib Isethionate-019、(VII)965082-1-a、(XXII)805433-1-b、(IX)919110-1-a,(IX)919110-1-b
应用背景（按来源药适应症）
乳腺癌羟乙磺酸达尔西利转移性乳腺癌羟乙磺酸达尔西利前列腺癌羟乙磺酸达尔西利三阴性乳腺癌羟乙磺酸达尔西利脑膜瘤羟乙磺酸达尔西利肝功能衰退羟乙磺酸达尔西利边缘带B细胞淋巴瘤奥布替尼套细胞淋巴瘤奥布替尼慢性淋巴细胞白血病奥布替尼特发性血小板减少性紫癜奥布替尼系统性红斑狼疮奥布替尼多发性硬化奥布替尼特发性肺纤维化那米司特间质性肺疾病那米司特肺纤维化那米司特肌炎那米司特系统性硬皮病那米司特肌病那米司特非小细胞肺癌地罗阿克
来源药（使用该中间体的合成路线）
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one→tert-Butyl 4-[6-[(6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperidine-1-carboxylate→1-(Vinyloxy)butane→tert-Butyl 4-(6-[[6-(1-butoxyethenyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino]pyridin-3-yl)piperidine-1-carboxylate→tert-Butyl 4-[6-[(6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperidine-1-carboxylate→2-Hydroxyethane-1-sulfonic acid 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperidin-4-yl)pyridin-2-yl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one→2-Amino-6-bromo-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one→2-Amino-6-(1-butoxyethenyl)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one→tert-Butyl 6-chloro-3',6'-dihydro[3,4'-bipyridine]-1'(2'H)-carboxylate→5-Bromo-2-chloropyridine→tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate→tert-Butyl 6-[[6-(1-butoxyethenyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino]-3',6'-dihydro[3,4'-bipyridine]-1'(2'H)-carboxylate
2,6-Dichloronicotinonitrile→2,6-Dichloronicotinamide→2,6-Dichloropyridine-3-carboxylic acid→(3-Phenoxyphenyl)boronic acid→4,4,5,5-Tetramethyl-2-(3-phenoxyphenyl)-1,3,2-dioxaborolane→6-Chloro-2-(4-phenoxyphenyl)pyridine-3-carboxamide→N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester→tert-Butyl 5-carbamoyl-6-(4-phenoxyphenyl)-3',6'-dihydro[2,4'-bipyridine]-1'(2'H)-carboxylate→tert-Butyl 4-[5-carbamoyl-6-(4-phenoxyphenyl)pyridin-2-yl]piperidine-1-carboxylate→2-(4-Phenoxyphenyl)-6-(piperidin-4-yl)pyridine-3-carboxamide→2-(4-Phenoxyphenyl)-6-(piperidin-4-yl)pyridine-3-carboxamide hydrogen chloride→Acryloyl chloride
5-Chloro-2-(piperidin-4-yl)pyrimidine hydrogen chloride→4-Methylbenzene-1-sulfonic acid 5-chloro-2-(piperidin-4-yl)pyrimidine→5-Chloro-2-(piperidin-4-yl)pyrimidine sulfate→4-(5-Chloropyrimidin-2-yl)piperidin-1-ium hexafluoridophosphate(1-)→2,4,5-Trichloropyrimidine→4-Piperidinecarbonitrile→Methyl piperidine-4-carboximidate hydrogen chloride→Piperidine-4-carboximidamide→Piperidine-4-carboximidamide hydrogen chloride→2-Chloro-1,3-bis(dimentylamino)trimethinium hexafluorophosphate→2,5-Dichloropyrimidine→5-Chloro-2-iodopyrimidine→(1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester→Boc-4-(5-chloropyrimidin-2-yl)-3,6-dihydropyridine→Boc-4-(5-chloropyrimidin-2-yl)piperidine
2-Hydroxy-5-methylanisole→2-Methoxy-4-methyl-6-nitrophenol→5-Methyl-3-nitrobenzene-1,2-diol→1,2-Dibromoethane→7-Methyl-5-nitro-2,3-dihydro-1,4-benzodioxine→6-Bromo-7-methyl-5-nitro-2,3-dihydro-1,4-benzodioxine→6-Bromo-7-methyl-2,3-dihydro-1,4-benzodioxin-5-amine→6-Bromo-8-iodo-7-methyl-2,3-dihydro-1,4-benzodioxin-5-amine→(1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester→tert-Butyl 4-(8-amino-7-bromo-6-methyl-2,3-dihydro-1,4-benzodioxin-5-yl)-3,6-dihydropyridine-1(2H)-carboxylate→tert-Butyl 4-(8-amino-6-methyl-2,3-dihydro-1,4-benzodioxin-5-yl)piperidine-1-carboxylate→2,5-Dichloro-N-(2-((1-methylethyl)sulfonyl)phenyl)-4-pyrimidinamine→1-Amino-2-(isopropylsulphonyl)benzene→2,4,5-Trichloropyrimidine→tert-Butyl 4-(8-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-6-methyl-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperidine-1-carboxylate
7-Methyl-5-nitro-2,3-dihydro-1,4-benzodioxine→(1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester→tert-Butyl 4-(8-amino-6-methyl-2,3-dihydro-1,4-benzodioxin-5-yl)piperidine-1-carboxylate→7-Methyl-2,3-dihydro-1,4-benzodioxin-5-amine→8-Bromo-7-methyl-2,3-dihydro-1,4-benzodioxin-5-amine→tert-Butyl 4-(8-amino-6-methyl-2,3-dihydro-1,4-benzodioxin-5-yl)-3,6-dihydropyridine-1(2H)-carboxylate
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。