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CAS 74-89-5
AminomethaneMethylamine
登记编号：(X)819703-1-a、(X)819703-2-a、(VI)819703-3-a、Ephedrine Sulfate-005、Lercanidipine Hydrochloride-021、Phenylephrine Hydrochloride-038、Pilocarpine Nitrate-013、(II)275500-4-a、(VI)275500-5-a、(VI)275500-6-a、Granisetron-020
应用背景（按来源药适应症）
胃肠道间质瘤瑞派替尼低血压硫酸麻黄碱原发性高血压缬沙坦/盐酸乐卡地平感冒布洛芬/盐酸去氧肾上腺素发热布洛芬/盐酸去氧肾上腺素头痛布洛芬/盐酸去氧肾上腺素青光眼盐酸普索洛尔/盐酸毛果芸香碱高血压盐酸乐卡地平瞳孔散大盐酸去氧肾上腺素低血压盐酸去氧肾上腺素睫状肌麻痹盐酸去氧肾上腺素室上性心动过速盐酸去氧肾上腺素休克盐酸去氧肾上腺素缺血性卒中盐酸去氧肾上腺素闭角型青光眼盐酸毛果芸香碱高眼压盐酸毛果芸香碱开角型青光眼盐酸毛果芸香碱瞳孔缩小盐酸毛果芸香碱Sjtoegren综合征盐酸毛果芸香碱虹膜炎盐酸毛果芸香碱过敏反应肾上腺素鼻喷雾剂（ARS Pharmaceuticals）慢性荨麻疹肾上腺素鼻喷雾剂（ARS Pharmaceuticals）荨麻疹肾上腺素鼻喷雾剂（ARS Pharmaceuticals）哮喘肾上腺素鼻喷雾剂（ARS Pharmaceuticals）呼吸道感染肾上腺素鼻喷雾剂（ARS Pharmaceuticals）化疗导致的恶心和呕吐格拉司琼恶心格拉司琼呕吐格拉司琼手术后恶心呕吐格拉司琼术后疼痛格拉司琼胃肌轻瘫格拉司琼
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 瑞派替尼Ripretinib | Tier C · 观察 / 贸易 | 2032 |
| 硫酸麻黄碱Ephedrine Sulfate | Tier C · 观察 / 贸易 | - |
| 缬沙坦/盐酸乐卡地平Valsartan/Lercanidipine Hydrochloride | Tier C · 观察 / 贸易 | - |
| 布洛芬/盐酸去氧肾上腺素Ibuprofen/Phenylephrine Hydrochloride | Tier C · 观察 / 贸易 | - |
| 盐酸普索洛尔/盐酸毛果芸香碱Proxodolol hydrochloride/Pilocarpine Hydrochloride | Tier C · 观察 / 贸易 | - |
| 盐酸乐卡地平Lercanidipine Hydrochloride | Tier C · 观察 / 贸易 | - |
| 盐酸去氧肾上腺素Phenylephrine Hydrochloride | Tier C · 观察 / 贸易 | - |
| 盐酸毛果芸香碱Pilocarpine Hydrochloride | Tier C · 观察 / 贸易 | - |
| 肾上腺素鼻喷雾剂（ARS Pharmaceuticals）Epinephrine intranasal spray (ARS Pharmaceuticals) | Tier C · 观察 / 贸易 | - |
| 格拉司琼Granisetron | Tier C · 观察 / 贸易 | - |
| 氢溴酸依他佐辛Eptazocine hydrobromide | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
1,3-Acetonedicarboxylic acid diethyl ester→4,6-Dihydroxynicotinic acid ethyl ester→2,4-Dichloro-5-carbethoxypyridine→Aminoethane→6-Chloro-4-ethylamino-nicotinic acid ethyl ester→[6-Chloro-4-(ethylamino)pyridin-3-yl]methanol→6-Chloro-4-(ethylamino)nicotinaldehyde→Ethyl (5-amino-2-bromo-4-fluorophenyl)acetate→3-(5-Amino-2-bromo-4-fluorophenyl)-7-chloro-1-ethyl-1,6-naphthyridin-2(1H)-one→Aminomethane→3-(5-Amino-2-bromo-4-fluorophenyl)-1-ethyl-7-(methylamino)-1,6-naphthyridin-2(1H)-one→3-(5-Amino-2-bromo-4-fluorophenyl)-1-ethyl-7-(methylamino)-1,6-naphthyridin-2(1H)-one hydrochloride→4-Isocyanatobenzene→Carbanilic acid phenyl ester→2-(2-Bromo-4-fluorophenyl)acetic acid→(2-Bromo-4-fluoro-5-nitrophenyl)acetic acid→Ethyl (2-bromo-4-fluoro-5-nitrophenyl)acetate
Methyl (2-bromo-4-fluoro-5-nitrophenyl)acetate→6-Chloro-4-nitropyridine-3-carbaldehyde→Methyl (2Z)-2-(2-bromo-4-fluoro-5-nitrophenyl)-3-(6-chloro-4-nitropyridin-3-yl)prop-2-enoate→3-(5-Amino-2-bromo-4-fluorophenyl)-7-chloro-1,6-naphthyridin-2(1H)-one→Aminobenzene→1,1,1-Trichloromethanol 1,1'-carbonate→N-[4-Bromo-5-(7-chloro-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl]-N'-phenylurea→1-Iodoethane→N-[4-Bromo-5-(7-chloro-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl]-N'-phenylurea→Aminomethane
(2-Bromo-4-fluoro-5-nitrophenyl)acetic acid→Carbanilic acid phenyl ester→Ethyl [2-bromo-4-fluoro-5-[(phenylcarbamoyl)amino]phenyl]acetate→6-Chloro-4-(ethylamino)nicotinaldehyde→N-[4-Bromo-5-(7-chloro-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl]-N'-phenylurea→Aminomethane
Benzene→2-Chloropropanoyl chloride→2-Chloro-1-phenylpropan-1-one→alpha-Bromopropiophenone→Methylamine→2-(Methylamino)-1-phenylpropan-1-one→(2R,3R)-2,3-Bis(benzoyloxy)butanedioic acid (2S)-2-(methylamino)-1-phenylpropan-1-one (1/2)→(2R,3R)-2,3-Bis(benzoyloxy)butanedioic acid (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol (1/2)→(-)-2(S)-(Methylamino)-1(R)-phenylpropan-1-ol hydrochloride→(-)-2(S)-(Methylamino)-1(R)-phenylpropan-1-ol
Ethyl phenyl ketone→1-Phenylpropane-1,2-dione 2-oxime→(1R,2E)-2-(Hydroxyimino)-1-phenylpropan-1-ol→(1R)-1-Hydroxy-1-phenylpropan-2-one→Methylamine→(-)-2(S)-(Methylamino)-1(R)-phenylpropan-1-ol→Benzaldehyde→2-Oxopropionic acid
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。