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CAS 1191-95-3
cyclobutanoneCyclobutanone
登记编号：APAL-014、(I)992511-1-a,(I)992511-1-d
应用背景（按来源药适应症）
去势抵抗性前列腺肿瘤阿帕他胺前列腺癌阿帕他胺慢性淋巴细胞白血病利沙托克拉急性早幼粒细胞白血病利沙托克拉骨髓增生异常综合征利沙托克拉急性髓细胞样白血病利沙托克拉弥漫性大B-细胞淋巴瘤利沙托克拉系统性红斑狼疮利沙托克拉
来源药（使用该中间体的合成路线）
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
3-(trifluoromethyl)pyridin-2-ol→5-iodo-3-(trifluoromethyl)pyridin-2-ol→2-chloro-5-iodo-3-(trifluoromethyl)pyridine→(4-methoxyphenyl)methanamine→6-chloro-N-(4-methoxybenzyl)-5-(trifluoromethyl)pyridin-3-amine→5-((4-methoxybenzyl)amino)-3-(trifluoromethyl)picolinonitrile→5-amino-3-(trifluoromethyl)picolinonitrile→5-isothiocyanato-3-(trifluoromethyl)picolinonitrile→4-((1-cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide→2,4-difluorobenzoyl chloride→2,4-difluoro-N-methylbenzamide→2-fluoro-4-((4-methoxybenzyl)amino)-N-methylbenzamide→4-amino-2-fluoro-N-methylbenzamide→cyclobutanone
Cyclobutanone→1-(Triphenylphosphoranylidene)-2-propanone→1-Cyclobutylidenepropan-2-one→Carbonic acid dimethyl diester→Spiro[3.5]nonane-6,8-dione→8-(2-Methylpropoxy)spiro[3.5]non-7-en-6-one→Spiro[3.5]non-7-en-6-one→Spiro[3.5]nonan-6-one→1,3-Dimethyl propanedioate→Methyl 6-oxospiro[3.5]nonane-7-carboxylate→Methyl 6-(((trifluoromethyl)sulfonyl)oxy) spiro[3.5]non-6-ene-7-carboxylate→(4-Chlorophenyl)boranediol→Methyl 6-(4-chlorophenyl)spiro[3.5]non-6-ene-7-carboxylate→[6-(4-Chlorophenyl)spiro[3.5]non-6-en-7-yl]methanol→7-(Chloromethyl)-6-(4-chlorophenyl)spiro[3.5]non-6-ene
Cyclobutanone→Spiro[3.5]nonane-6,8-dione→Spiro[3.5]nonan-6-one→(4-Chlorophenyl)boranediol→1-(1,1-Dimethylethoxycarbonyl)piperazine→6-Chlorospiro[3.5]non-6-ene-7-carbaldehyde→(Diethoxyphosphinyl)acetic acid ethyl ester→Ethyl cyclobutylideneacetate→1,3-Acetonedicarboxylic acid diethyl ester→Formyldimethylamine→6-(4-Chlorophenyl)spiro[3.5]non-6-ene-7-carbaldehyde→N-Boc-1-[[8-(4-chlorophenyl)spiro[3.5]non-7-en-7-yl]methyl]piperazine→1-[[6-(4-Chlorophenyl)spiro[3.5]non-6-en-7-yl]methyl]piperazine dihydrogen chloride→1-[[6-(4-Chlorophenyl)spiro[3.5]non-6-en-7-yl]methyl]piperazine
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 | 操作 |
|---|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 5-Amino-3-(trifluoromethyl)picolinonitrile Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Nantong cGMP Site | N-Boc-1-aminocyclobutanecarboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — | |
| Unibest Taizhou GMP-like Site | 1-amino-N-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]Cyclobutanecarboxamide Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。